Phages infecting Faecalibacterium prausnitzii belong to novel viral genera that help to decipher intestinal viromes
Background Viral metagenomic studies have suggested a role for bacteriophages in
intestinal dysbiosis associated with several human diseases. However, interpretation of viral …
intestinal dysbiosis associated with several human diseases. However, interpretation of viral …
Expanding known viral diversity in the healthy infant gut
The gut microbiome is shaped through infancy and impacts the maturation of the immune
system, thus protecting against chronic disease later in life. Phages, or viruses that infect …
system, thus protecting against chronic disease later in life. Phages, or viruses that infect …
[HTML][HTML] Massive expansion of human gut bacteriophage diversity
LF Camarillo-Guerrero, A Almeida, G Rangel-Pineros… - Cell, 2021 - cell.com
Bacteriophages drive evolutionary change in bacterial communities by creating gene flow
networks that fuel ecological adaptions. However, the extent of viral diversity and its …
networks that fuel ecological adaptions. However, the extent of viral diversity and its …
Metagenome data on intestinal phage-bacteria associations aids the development of phage therapy against pathobionts
K Fujimoto, Y Kimura, M Shimohigoshi, T Satoh… - Cell host & …, 2020 - cell.com
The application of bacteriophages (phages) is proposed as a highly specific therapy for
intestinal pathobiont elimination. However, the infectious associations between phages and …
intestinal pathobiont elimination. However, the infectious associations between phages and …
[HTML][HTML] New insights into intestinal phages
The intestinal microbiota plays important roles in human health. This last decade, the viral
fraction of the intestinal microbiota, composed essentially of phages that infect bacteria …
fraction of the intestinal microbiota, composed essentially of phages that infect bacteria …
Probing the “dark matter” of the human gut phageome: Culture assisted metagenomics enables rapid discovery and host-linking for novel bacteriophages
CB Fitzgerald, AN Shkoporov, A Upadrasta… - Frontiers in cellular …, 2021 - frontiersin.org
Recent years have been marked by the growing interest towards virulent and temperate
bacteriophage populations inhabiting the human lower gastrointestinal tract–the gut …
bacteriophage populations inhabiting the human lower gastrointestinal tract–the gut …
Broad host range may be a key to long-term persistence of bacteriophages infecting intestinal Bacteroidaceae species
S Hedžet, M Rupnik, T Accetto - Scientific reports, 2022 - nature.com
The longitudinal studies have found that the human gut microbiota is stable over time with
some major bacterial lineages or even strains persisting for years. This was recently …
some major bacterial lineages or even strains persisting for years. This was recently …
Large-scale phage cultivation for commensal human gut bacteria
Phages are highly abundant in the human gut, yet most of them remain uncultured. Here, we
present a gut phage isolate collection (GPIC) containing 209 phages for 42 commensal …
present a gut phage isolate collection (GPIC) containing 209 phages for 42 commensal …
Comparative (meta) genomic analysis and ecological profiling of human gut-specific bacteriophage φB124-14
Bacteriophage associated with the human gut microbiome are likely to have an important
impact on community structure and function, and provide a wealth of biotechnological …
impact on community structure and function, and provide a wealth of biotechnological …
Murine colitis reveals a disease-associated bacteriophage community
The dysregulation of intestinal microbial communities is associated with inflammatory bowel
diseases (IBD). Studies aimed at understanding the contribution of the microbiota to …
diseases (IBD). Studies aimed at understanding the contribution of the microbiota to …