Adjuvants are crucial components of vaccines. They significantly improve vaccine efficacy by
modulating, enhancing, or extending the immune response and at the same time reducing …

Adjuvants are critical components of many vaccines. The majority of existing vaccines
contain a single adjuvant. Owing to their inherent limitations, no single adjuvant is capable …

Research on new adjuvants and delivery systems has expanded dramatically in the last
decade. New generation vaccines, based on recombinant proteins, synthetics, and …

Adjuvants are essential components of most clinically used vaccines. This is because the
majority of nonliving vaccines are relatively poor inducers of adaptive immunity unless …

Vaccines are one of the most significant medical interventions in the fight against infectious
diseases. Since their discovery by Edward Jenner in 1796, vaccines have reduced the …

Introduction: Adjuvants form an integral component in most of the inactivated and subunit
vaccine formulations. Careful and proper selection of adjuvants helps in promoting …

Abstract Formulation science is an unappreciated and often overlooked aspect in the field of
vaccinology. In this review we highlight key attributes necessary to generate well …

Adjuvants enhance immunity to vaccines and experimental antigens by a variety of
mechanisms. In the past decade, many receptors and signaling pathways in the innate …

Key concepts n Adjuvantation of vaccines is a well-established concept and practice n
Adjuvants enhance and modulate immune responses to antigens. This is particularly …

Vaccines were first introduced more than 200 years ago and have since played a key role in
the reduction of morbidity and mortality caused by infectious diseases. Many of the safest …