… of age or differences in longevity between species? We find that DNAm can predict the age
of individual bats with high accuracy. At the species level, the rate of change in DNAm at age-…

… differ in lifespan. Here, we use DNA methylation (DNAm) profiles from 712 known-age bats,
… Bats have great potential for providing insight into mechanisms that reduce deleterious …

… Here, we use DNA methylation (DNAm) as an epigenetic … if epigenetic age, as predicted by
a multi-species bat epigenetic clock, … of sites associated with differences in bat longevity [25]. …

… ageing, bats are mammals with remarkable longevity despite … and long-lived bats Myotis
lucifugus as predicted by the free … as humans, age-related changes in DNA methylation were …

… lifespan has increased, we reconstructed the longevity quotient (LQ), ie the ratio of observed
to predicted longevity, … We predicted bat longevity by least-squares regression, ie log 10 (…

… (2021) compared DNA methylation (DNAm) profiles across 26 bat species to … age and
longevity. This study showed that DNAm accurately predicts chronological age, and that longevity …

… Bats also exhibit extreme longevity given … DNA methylation (DNAm) from wing biopsies in
26 bat species, found that DNAm generated from 150 CpG sites can predict chronological age …

… targets for DNA methylation, is correlated with lifespan. Using … of a model that can predict
lifespan accurately from only a … This would also provide insight into other variables which may …

… Below I discuss how the results from the two different methods used provide insight into the
… DNA methylation predicts age and provides insight into exceptional longevity of bats. Nature …

… derive DNA methylation (DNAm) predictors of maximum life span (R = 0.89), gestation time
(R = 0.96), and age at … Our study on predicting maximum life span did not incorporate DNA …