… With Heart Failure) trial comprised 2 randomized, placebo-controlled trials of heart failure—…
with HFpEF—which investigated the effects of dapagliflozin on KCCQ Total Symptom Score …

… Treatments for heart failure that work through neurohumoral … tRial in patients with chrOnic
heaRt failure (EMPEROR) trials … analyses of the effects of dapagliflozin across the full range of …

… sacubitril/valsartan and sodium-glucose cotransporter-2 (SGLT-2) inhibitor dapagliflozin
have been shown to reduce rehospitalization and cardiac mortality in patients with heart failure (…

… is mainly attributed to the combined effects of dapagliflozin on the cardiovascular system
and … Overall, the cardioprotective effects of dapagliflozin and the reduction in the risk of HF …

… Both the DAPA-HF and DEFINE-HF trials were published at the same time; yet, the
DEFINE-HF study focused on the effects of dapagliflozin on symptoms, functional status, and …

… of the Cardiac and Metabolic Effects of Dapagliflozin in Heart Failure With Preserved Ejection
… This secondary analysis evaluates the effects of dapagliflozin on pulsatile pulmonary …

… This systematic review and meta-analysis aimed to assess the comparative effects of
dapagliflozin versus placebo in patients with heart failure, with a primary focus on functional …

… effects of dapagliflozin against heart failure with reduced ejection fraction (HFrEF) or heart
failure … area), we confirm the predominant effects of dapagliflozin relied on macrophages and …

… in 6263 patients with heart failure and mildly reduced or preserved ejection fraction. In a
follow-up meta-analysis of DAPA-HF and DELIVER, the effects of dapagliflozin were consistent …

… Heart failure (HF) is associated with a high morbidity and mortality burden. In light of more …
these benefits, particularly the positive effects of dapagliflozin on reversing cardiac (atrial and …