… acetylation can encompass other types of protein acetylation, such as amino-terminal protein
acetylation and O-linked acetylation of … 50 . Proliferating cell nuclear antigen (PCNA) is also …

… The research history of protein acetylation has spanned >50 years. Lysine … and
lysosome-related gene expression, can be acetylated by GCN5 at K274 and K279 in the way of Nε-…

… , tissue injury and metabolic stress. We propose a … acylation is regulated by the metabolism
of the different acyl-CoA forms, which in turn modulates the regulation of gene expression. …

… Histone acetylation and non-histone protein acetylation influence a myriad of … We begin
by describing the influence of histone acetylation on … Gene regulation by histone acetylation …

… cellular regulatory molecule with diverse functions beyond the … , which links mitochondrial
metabolism to a wide array of … to enzyme and gene regulation through protein acetylation. It …

… Protein acetylation occurs both cotranslationally onto the N-… activate or repress gene
expression depending on which … of these reactions, factors beyond deacetylation need to be …

… with a global 50%–70% increase in histone acetylation over … on the epigenetic regulation
of gene expression. … Most of these newer adducts in Figure 1 are beyond the remit …

… targeted protein acetylation reactions that can regulate central … plays in transcriptional
regulation and cancer metabolism. … of 9 years of follow-up of a large group of people aged 50–71, …

… we refer to as epigenetic modifications, together form the epigenome and are linked to gene
regulation and thus to … Each modification is derived from intermediates from metabolism. …

… In this case, acetylation generally correlates with gene expression, acting in part to ‘open
up’ chromatin for appropriate transcriptional machinery to access the DNA template. We now …