… Earlier studies have found numerous ageing changes within cancer-related genes and
we also find many genes in this category, including previously identified loci in CDKN2A (also …

… in the present study as being aging-associated (Tables 1 and 2; Additional file 3: Table S4).
However, a recent meta-analysis on three DNAmet data sets obtained using 450BeadChip …

… Genes around these CpG sites have been reported to be involved in the ageing process. …
a series of genome-wide association studies by using the random effects as the dependent …

… Finally, our study shows that large-scale integrative genomics studies are an effective
approach toward the identification of fundamental processes involved in ageing and are …

… Earlier studies have found numerous ageing changes within cancer-related genes and we
… Massively parallel quantification of the regulatory effects of noncoding genetic variation in a …

… the role of DNA methylation in aging. The first three studies in this thesis focus on different
mechanisms of DNA methylation related to aging, including methylation level, methylation …

… chromosomal dosage, differences in ageing-associated DNA methylation changes in … ageing.
While age-associated CpGs showed good replication across datasets in the present study, …

… Aging and expansion of BM-MSCs induce epigenetic changes that can … sequencing-based
methods, we reveal that the breadth of DNA methylation dynamics associated with aging and …

… be indicative of biological aging. In this study, we aimed for a better understanding of how
epigenetic age predictions are associated with life expectancy in the ESTHER study cohort, a …

… diseases because in addition to the sequence variation they may show individual differences
in DNA methylation. We performed methylome-wide association studies (MWAS) to test …