Progress in the development of subunit vaccines against malaria

M Skwarczynski, S Chandrudu, B Rigau-Planella… - Vaccines, 2020 - mdpi.com
… falciparum AMA-A- and CSP-derived peptides as a malaria vaccine, ten Tanzanian adults
… living in a malaria-endemic region were immunized with one or two doses of the vaccine on …

RTS, S: the first malaria vaccine

F Zavala - The Journal of clinical investigation, 2022 - Am Soc Clin Investig
… consensus that major improvements are necessary to develop a vaccine that is likely to have
a greater epidemiological impact in endemic areas. Since the development of RTS,S in the …

Advances in malaria vaccine development: report from the 2017 malaria vaccine symposium

CH Coelho, JYA Doritchamou, I Zaidi, PE Duffy - npj Vaccines, 2017 - nature.com
… many areas without a vaccine. Malaria vaccines have long been a research priority, but only
this year the World Health Organization announced that a malaria vaccine would advance …

[HTML][HTML] The RH5-CyRPA-Ripr complex as a malaria vaccine target

RJ Ragotte, MK Higgins, SJ Draper - Trends in parasitology, 2020 - cell.com
A highly effective malaria vaccine would be one way to achieve further reductions in the global
malaria … confers immunity against malaria suggests that a malaria vaccine is conceivable [ …

Malaria vaccines: from the past towards the mRNA vaccine era

ME Tsoumani, C Voyiatzaki, A Efstathiou - Vaccines, 2023 - mdpi.com
… features, including their potential for rapid development, scalability, and flexibility in
antigen design, make them a promising avenue for malaria vaccine development. This review …

Malaria vaccines since 2000: progress, priorities, products

PE Duffy, J Patrick Gorres - npj Vaccines, 2020 - nature.com
Malaria vaccine development entered a new era in 2015 … the first human anti-parasite
vaccine to pass regulatory scrutiny. … of vaccines for malaria elimination, or a so-called vaccine to …

Malaria vaccines: a new era of prevention and control

PE Duffy, JP Gorres, SA Healy, M Fried - Nature Reviews Microbiology, 2024 - nature.com
… We explore next-generation vaccines designed using new knowledge of malariaa
decision-making process that prioritizes malaria vaccine candidates for development in a

RTS, S malaria vaccine and increased mortality in girls

SL Klein, F Shann, WJ Moss, CS Benn, P Aaby - MBio, 2016 - Am Soc Microbiol
… published a position paper on malaria vaccines (2), with emphasis on the RTS,S/AS01 …
also was a tendency for RTS,S to be associated with a higher risk of fatal malaria in girls (malaria

A monoclonal antibody for malaria prevention

…, O Trofymenko, Z Hu, A Campos Chagas… - … England Journal of …, 2021 - Mass Medical Soc
… Here, we present evidence in humans that malaria can be prevented from 4 to 36 weeks
after a single administration of a monoclonal antibody against the major protein covering the …

Novel malaria vaccines

MB Laurens - Human Vaccines & Immunotherapeutics, 2021 - Taylor & Francis
… no vaccine has been deployed for widespread use against a … The RTS,S/AS01 vaccine is
the first licensed malaria vaccine to … A novel approach that can be studied for malaria vaccines