… to predict static combination therapies that effectively address heterogeneity in a lymphoma
… of cancer heterogeneity and evolution. The application of optimal control theory to treatment …

… score was an independent predictor of an increased disease … addressed this question
with regard to TP53 alterations … are composed of a heterogeneous mix of genomic alterations…

… predictive cancer models and inform therapeutic strategies. … we highlight ongoing
computational efforts in addressing the … using a combination of metadata (for example, age, tumor …

… of modern oncology, including the static tumor homogeneity and single biopsy-guided …
sensitivity prediction and development of a drug bank to successfully address extensive genetic, …

… Moreover, using patient specific information from bone metastatic specimens, we … the HCA
model in predicting the efficacy of TGFβ inhibitors on lesions that are heterogeneous for TGFβ …

… -art computational approaches for drug combination prediction, … Cocktail of drugs addresses
combination of more than two … Intra-tumor heterogeneity observed in many cancer types also …

… intra-tumor heterogeneity by using mutations from bulk … -related features are associated to
or predictive for some clinical … and treatment, but there still challenges to be addressed. First…

… to the ability of combinations to address tumor heterogeneity, but … Understanding response
heterogeneity could reveal predictive … Moreover, computational methods attempting to predict …

… for positivity and addressing whether optimum thresholds for … from these agents and to
tailor ICI combinations. Many … Computational neoantigen prediction pipelines have been …

… tumour information layers like intra-tumour heterogeneity (ITH) … computational efforts to
consider ITH on choosing therapies … Next, we wanted to address if this result is biased by EGFR …