Aging as a biological target for prevention and therapy

N Barzilai, AM Cuervo, S Austad - Jama, 2018 - jamanetwork.com
Chronic health problems related to the unprecedented aging of the human population in the
21st century threaten to disrupt economies and degrade the quality of later life throughout
the developed world. Fortunately, research has shown that fundamental aging processes
can be targeted by nutritional, genetic, and pharmacologic interventions to enhance and
extend both health and longevity in experimental animal models. These findings clearly
demonstrate that the biological rate of aging can be slowed. Thegerosciencehypothesis, forwhichthereisabundantevidenceinanimal …
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