process in which endothelial dysfunction is important. Emerging evidence suggests that
arginase is a key mediator of endothelial dysfunction in type 2 diabetes mellitus by
reciprocally regulating nitric oxide bioavailability. The aim of this prospective intervention
study was to test the hypothesis that arginase activity is increased and that arginase
inhibition improves microvascular endothelial function in patients with type 2 diabetes and …