Characterising sex differences of autosomal DNA methylation in whole blood using the Illumina EPIC array

OA Grant, Y Wang, M Kumari, NR Zabet… - Clinical epigenetics, 2022 - Springer
… Here, we report for the first time an analysis of autosomal sex differences in DNAme using
the … and determine patterns of global DNA methylation levels between males and females. …

A cross-cohort analysis of autosomal DNA methylation sex differences in the term placenta

AM Inkster, V Yuan, C Konwar, AM Matthews… - … of sex differences, 2021 - Springer
… To investigate whether female (XX) and male (XY) term placentae had different global …
DNAme by whole-genome oxidative bisulfite sequencing identified that male placentae are on the …

Autosomal sex-associated co-methylated regions predict biological sex from DNA methylation

E Gatev, AM Inkster, GL Negri, C Konwar… - Nucleic Acids …, 2021 - academic.oup.com
… were robust and not affected by outliers or differences in coverage between DNAm technologies,
we restricted our analysis to datasets of at least 50 male and 50 female DNAm profiles …

Sex-associated autosomal DNA methylation differences are wide-spread and stable throughout childhood

M Suderman, A Simpkin, G Sharp, T Gaunt, O Lyttleton… - Biorxiv, 2017 - biorxiv.org
differences in DNA methylation between male and femaleanalysis of testosterone levels on
the DNA methylation sex … site or discordance with whole genome bisulfite sequencing (101). …

[HTML][HTML] Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation

O Solomon, K Huen, P Yousefi, LK Küpers… - … Research/Reviews in …, 2022 - Elsevier
… We report novel findings of autosomal methylation differences between males and females
using robust statistical models with a large sample size that was well-powered to assess …

Exploratory analysis of age and sex dependent DNA methylation patterns on the X-chromosome in whole blood samples

S Li, JB Lund, K Christensen, J Baumbach… - Genome Medicine, 2020 - Springer
male genomes. As an explanation, we estimated higher variability in autosomal DNA methylation
in males than that in females … techniques such as whole genome bisulfite sequencing …

Characterizing the dynamic and functional DNA methylation landscape in the developing human cortex

KA Perzel Mandell, AJ Price, R Wilton… - Epigenetics, 2021 - Taylor & Francis
… In the present report, we use whole-genome bisulfite … We also find that there are autosomal
differences in DNAm between the … There were 10 of each male and female subjects, and 17 …

Sex differences in the intergenerational link between maternal and neonatal whole blood DNA methylation: a genome-wide analysis in 2 birth cohorts

J Hu, X Xu, J Li, Y Jiang, X Hong, KM Rexrode… - Clinical …, 2023 - Springer
whole genome using data from a published study on DNAm quantitative trait loci [25], but
only the heritability of autosomal … finding that differences in mother–female methylation levels …

Evaluation of genome-wide DNA methylation profile of human embryos with different developmental competences

M Yang, X Tao, K Scott, Y Zhan, RT Scott Jr… - Human …, 2021 - academic.oup.com
DNA methylome analysis for human embryo trophectoderm biopsies using whole-genome
To obtain the copy number estimate, this result was multiplied by 2 for autosomes or by 1 for …

[HTML][HTML] Age-related DNA methylation changes are sex-specific: a comprehensive assessment

I Yusipov, MG Bacalini, A Kalyakulina… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
… When considering autosomal differences in DNA methylation between men and women (…
The analysis of sex- and age-dependent DNA methylation on sex chromosomes poses …