Applications of blockchain technology in clinical trials: review and open challenges

IA Omar, R Jayaraman, K Salah, I Yaqoob… - Arabian Journal for …, 2021 - Springer
… is a blockchain-based document management solution that has … to solve numerous
economic, organizational, and technicalfeatures of blockchain help to improve clinical trial data

Big data management challenges in health research—a literature review

X Wang, C Williams, ZH Liu… - Briefings in …, 2019 - academic.oup.com
features of two fundamentally different data management … Fourth, to maximize the utility of
clinical research data and … impact on technical solutions in health research data management, …

… to enhance clinical data management using non-commercial and open source solutions across a multi-center network supporting inpatient pediatric care and research …

T Tuti, M Bitok, C Paton, B Makone… - … American Medical …, 2016 - academic.oup.com
… of CDM for a clinical trial. OpenClinica was implemented for a … feature we opted to explore
the use of Research Electronic … The technical team did not undertake a comprehensive review

Adaptive design: a review of the technical, statistical, and regulatory aspects of implementation in a clinical trial

FP Cerqueira, AMC Jesus, MD Cotrim - Therapeutic innovation & …, 2020 - Springer
research aims at compiling the technical, statistical, and regulatory implications of the employment
of adaptive design in a clinical trial… from trials that included basic study characteristics, …

Risk based monitoring (RBM) tools for clinical trials: a systematic review

C Hurley, F Shiely, J Power, M Clarke… - … clinical trials, 2016 - Elsevier
… or was provided to us to allow sufficient details about the tool to be included in this review. …
Risk is evaluated at each trial centre by the data manager according to set risk then Marvin (…

[图书][B] Data monitoring committees in clinical trials: a practical perspective

SS Ellenberg, TR Fleming, DL DeMets - 2019 - books.google.com
… We have attempted to keep the material non-technical, so as … arise in the review of
accumulating data from clinical trials. … popular, probably because its properties reflect the thinking …

OpenTrials: towards a collaborative open database of all available information on all clinical trials

B Goldacre, J Gray - Trials, 2016 - Springer
… We are keen to hear from anyone with suggestions, feature … in humans; however, because
this is principally a technical … a systematic review or a registry), we will extract some data from …

Sharing and reuse of individual participant data from clinical trials: principles and recommendations

C Ohmann, R Banzi, S Canham, S Battaglia, M Matei… - BMJ open, 2017 - bmjopen.bmj.com
… of data management and sharing within European researchdetails on the repositories
available, similar to the data … -reviewed papers and the registries that include details of the …

[HTML][HTML] Artificial intelligence for clinical trial design

S Harrer, P Shah, B Antony, J Hu - Trends in pharmacological sciences, 2019 - cell.com
… to a trial in time, as well as a lack of technical infrastructure to cope … These capabilities can
be used for correlating large and … clinical trial design is provided in a recent review by Fogel [ …

A review of big data and medical research

M Mallappallil, J Sabu, A Gruessner… - SAGE open …, 2020 - journals.sagepub.com
… include clickstream data, machine to machine data processing, geo-spatial data, audio and
… , which allows for optimization of product features for its advertising performance; additionally…