[HTML][HTML] Navigating multi-scale cancer systems biology towards model-driven clinical oncology and its applications in personalized therapeutics

MN Gondal, SU Chaudhary - Frontiers in Oncology, 2021 - frontiersin.org
… an intuitive framework modeling paradigm, the … ContraCancrum aimed to construct a
multi-scale computational framework for translating personalized cancer models into clinical

Navigating Multi-scale Cancer Systems Biology towards Model-driven Personalized Therapeutics

MN Gondal, SU Chaudhary - bioRxiv, 2021 - biorxiv.org
… an intuitive framework modeling paradigm, however, … ContraCancrum aimed to develop
a multi-scale computational framework for translating personalized cancer models into clinical

[HTML][HTML] Multi-scale network targeting: A holistic systems-biology approach to cancer treatment

D Paul, NL Komarova - Progress in biophysics and molecular biology, 2021 - Elsevier
… The model of cancer as a multidimensional spatio-temporal network … multi-scale interventions
may represent a paradigm shift that may guide the way we understand and treat cancer in …

[HTML][HTML] The INTEGRATE project: delivering solutions for efficient multi-centric clinical research and trials

H Kondylakis, B Claerhout, M Keyur, L Koumakis… - Journal of biomedical …, 2016 - Elsevier
… of multi-scale biomedical data in the context of post-genomic clinical trials, the development
of predictive models … execution of postgenomic multi-centric clinical trials in breast cancer. …

Mathematical Oncology to Cancer Systems Medicine: Translation from Academic Pursuit to Individualized Therapy with MORA

D Majumder - Current Cancer Therapy Reviews, 2023 - ingentaconnect.com
Clinically Driven Models Multi-scale cancer model was designed using clinical data from
non-small cell lung cancer and glioblastoma by bringing together basic science and …

E-Science technologies in a workflow for personalized medicine using cancer screening as a case study

O Spjuth, A Karlsson, M Clements… - Journal of the …, 2017 - academic.oup.com
… STHLM3 model (S3M), for predicting a man’s risk of having clinically significant prostate
cancer (… If successful, the WISDOM study could provide a paradigm shift, with a decrease in the …

[HTML][HTML] … of the in vivo antitumor efficacy of cisplatin-based doublet therapy in non-small cell lung cancer (NSCLC) through a multiscale mechanistic model

E Kolokotroni, D Dionysiou, C Veith… - PLoS Computational …, 2016 - journals.plos.org
… Multilevel Modeling’, FP7-ICT-2007-2-223979, http://contracancrum.eu/). Pseudonomized
data from the patients and tumor tissue of the Contra Cancrum project were used according to …

Efficient model of tumor dynamics simulated in multi-GPU environment

A Kłusek, M Łoś, M Paszyński… - … International Journal of …, 2019 - journals.sagepub.com
… 3-D tumor model of cancer dynamics, which employs classical numerical engine based on
the finite … (2016b) PAM: Particle Automata in modeling of multi-scale biological systems. ACM …

Clinical implications of in silico mathematical modeling for glioblastoma: a critical review

M Protopapa, A Zygogianni, GS Stamatakos… - Journal of neuro …, 2018 - Springer
… Stamatakos’ group runs the very ambitious ContraCancrum project, a computational oncology
environment that aims to integrate multi-scale cancer models in order to promote patient-…

[PDF][PDF] Efficient model of tumor progression simulated in multi-GPU environment

W Dzwinel, A Kłusek, M Łos, M Paszynski - researchgate.net
… 3D cancer model which allows for simulating both the growth and treatment phases of tumor
… PAM: Particle Automata in modeling of multi-scale biological systems, ACM Transactions on …