[HTML][HTML] Development of a Genetic Risk Score to predict the risk of overweight and obesity in European adolescents from the HELENA study

M Seral-Cortes, S Sabroso-Lasa, P De Miguel-Etayo… - Scientific reports, 2021 - nature.com
… considering body mass index (BMI… obesity risk in European adolescents with GRSs have
been conducted, the aim of the present study was to develop a GRS for overweight and obesity

[HTML][HTML] A computational framework for predicting obesity risk based on optimizing and integrating genetic risk score and gene expression profiles

PV Joseph, Y Wang, NH Fourie, WA Henderson - PLoS One, 2018 - journals.plos.org
… In this paper, we report a new mathematical method to predict obesity genetic risk. We … This
analysis indicates that the genetic risk score can significantly improve the obesity prediction …

[HTML][HTML] Genetic risk score for adult body mass index associations with childhood and adolescent weight gain in an African population

RJ Munthali, V Sahibdeen, J Kagura, LM Hendry… - Genes & nutrition, 2018 - Springer
obesity should begin early in life. The genetic risk score combined with other non-genetic
riskrisk of obesity and other related NCD risk factors in order to reduce the adverse health …

[HTML][HTML] Development of a Polygenic Risk Score for BMI to Assess the Genetic Susceptibility to Obesity and Related Diseases in the Korean Population

N Yoon, YS Cho - International Journal of Molecular Sciences, 2023 - mdpi.com
… aimed to develop a polygenic risk score (PRS) for BMI for predicting susceptibility to obesity
and … the model fit had the greatest R 2 score. The PRS BMI was tested for its association with …

[HTML][HTML] Impact of dietary and obesity genetic risk scores on weight gain

L Baratali, M Mean, P Marques-Vidal - The American Journal of Clinical …, 2021 - Elsevier
… (prospective analysis using a 5-y follow-up). We hypothesized that both dietary and obesity
GRS would be associated with obesity markers and weight gain, but that no significant gene-…

Genetic risk score enhances the risk prediction of severe obesity in adult survivors of childhood cancer

Y Sapkota, W Qiu, SB Dixon, CL Wilson, Z Wang… - Nature medicine, 2022 - nature.com
… at high risk for cardiovascular morbidity. Here we show the contribution of genetic risk scores
(… of childhood cancer who are at risk for severe obesity (body mass index ≥40 kg m − 2 ) as …

[HTML][HTML] Associations of genetic risk scores based on adult adiposity pathways with childhood growth and adiposity measures

C Monnereau, S Vogelezang, CJ Kruithof… - BMC genetics, 2016 - Springer
genetic risk score was associated with infant peak weight velocity, and the genetic risk scores
related to neuronal developmental … , membrane proteins, monogenic obesity and/or energy …

Weighting approaches for a genetic risk score and an oxidative stress score for predicting the incidence of obesity

S Park, HJ Yoo, SH Jee, JH Lee… - … Research and Reviews, 2020 - Wiley Online Library
… of obesity in a Korean population using a genetic risk score (GRS) constructed with
obesity-related single nucleotide polymorphisms (SNPs) along with an oxidative stress score (OSS). …

[HTML][HTML] Predicting anthropometric and metabolic traits with a genetic risk score for obesity in a sample of Pakistanis

S Rana, AA Bhatti - Scientific Reports, 2021 - nature.com
obesity is a polygenic trait indicating that multiple genetic variants act synergistically to influence
its expression. We constructed a genetic risk score (GRS) based on five geneticobesity-…

[HTML][HTML] Interplay of an obesity-based genetic risk score with dietary and endocrine factors on insulin resistance

O Ramos-Lopez, JI Riezu-Boj, FI Milagro, M Cuervo… - Nutrients, 2019 - mdpi.com
genetic makeup in the susceptibility for developing IR [34]. In this study, 16 obesity-related
genetic polymorphisms located at 13 genes … These genes participate in relevant physiological …