… factor promotes growth of neurons and neural stem cells possibly by triggering the phosphoinositide 3-kinase/AKT/glycogen synthase kinase-/β-catenin pathway

X Li, Z Liang, T Wang, J Yang, W Ma… - CNS & Neurological …, 2017 - ingentaconnect.com
… of differentiated cells via mitogenactivated protein kinase (MAPK)/extracellular regulated
Neuroprotection by NGF and BDNF against neurotoxin-exerted apoptotic death in neural …

[HTML][HTML] … induced by isoflurane anesthesia in aged rats via antioxidant, anti-inflammatory and anti-apoptotic effects mediated by the PI3K/AKT/GSK-3β pathway

Y Zhang, Z Zhang, H Wang, N Cai… - Molecular …, 2016 - spandidos-publications.com
apoptotic effects, mediated by the phosphoinositide 3‑kinase (PI3K)/AKT/glycogen synthase
kinase (GSK‑3β) pathway … -1 by negatively regulating GSK-3β to inhibit apoptosis (31). In …

… mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis

Y Jiang, F Liu, F Zou, Y Zhang, B Wang… - Stem cell research & …, 2019 - Springer
AKT/glycogen synthase kinase (GSK) 3β pathway regulates … the expression of SOX2, OCT4,
and NANOG; and modulates … hESCs and downregulated in differentiated cells [14]. As an …

… -derived brain-derived neurotrophic factor contributes to propofol-induced neuron death through Akt/glycogen synthase kinase 3β/mitochondrial fission pathway

Y Liu, Y Yan, Y Inagaki, S Logan… - Anesthesia & …, 2017 - journals.lww.com
pathway in developing neuronal death, whether astrocyte-derived BDNF regulates this pathway
to … In addition, the current study only used apoptotic cell death as an end point. Propofol …

Natural compounds regulate the PI3K/Akt/GSK3β pathway in myocardial ischemia-reperfusion injury

AH Ajzashokouhi, R Rezaee, N Omidkhoda, G Karimi - Cell Cycle, 2023 - Taylor & Francis
… GSK3β participates in some apoptotic signaling transduction by phosphorylating transcription
factors that regulate apoptosis; GSK3β induces activation of pro-apoptotic factors, such as …

Sevoflurane alleviates oxygen‑glucose deprivation/reoxygenation‑induced injury in HT22 cells through regulation of the PI3K/AKT/GSK3β signaling pathway

Q Yu, H Dai, Y Jiang, Y Zha… - Experimental and …, 2021 - spandidos-publications.com
… PI3K/AKT/glycogen synthase kinase (GSK3β) signaling … against cerebral ischaemia-induced
apoptosis (40). Therefore, we … the modulation of the PI3K/AKT/GSK3β signaling pathway. …

Loss of serine/threonine protein kinase 25 in retinal ganglion cells ameliorates high glucose-elicited damage through regulation of the AKT-GSK-3β/Nrf2 pathway

Z Zhou, H Li, S Bai, Z Xu, Y Jiao - Biochemical and Biophysical Research …, 2022 - Elsevier
… RGCs are terminally differentiated cells lacking regenerative … , including the AKT-glycogen
synthase kinase- (GSK-3β) axis … Importantly, this study identified STK25 as a new modulator

Glycogen synthase kinase-as a putative therapeutic target for bipolar disorder

MP Dandekar, SS Valvassori… - Current drug …, 2018 - ingentaconnect.com
… role in the regulation of apoptosis, synaptic plasticity, axon … GSK-3 acts as a central player
in modulating a diverse array … 1 regulates neuronal progenitor proliferation via modulation of …

INTRUSION OF GLYCOGEN SYNTHASE KINASE-TO COPE VARIOUS CARDIAC DISORDERS AT MOLECULAR LEVEL.

VV Kumar, AT Mahmood, M Anup, SR Kumar… - Indian …, 2020 - search.ebscohost.com
… activity in modulating the GSK-3β activity (table IV). … glycogen synthase kinase- (GSK-3β)
gene with differential … 3-kinase/Akt/glycogen synthase kinase 3beta signaling pathway, Mol. …

Protective effects of safranal on hypoxia/reoxygenation‑induced injury in H9c2 cardiac myoblasts via the PI3K/AKT/GSK3β signaling pathway

H Wang, B Zheng, K Che, X Han… - Experimental and …, 2021 - spandidos-publications.com
… /AKT/glycogen synthase kinase (GSK3β) axis is an intracellular signaling transduction
pathway … together to regulate apoptosis (63). Jayanthi et al (64) reported that the regulation of …