… Nutrients are actively taken up by the brain via various transporters at the blood–brain barrier
… Although it is known that the integrity of the BBB is altered during aging, the impact of aging …

… Accordingly, recent data confirm age-dependent deterioration of the blood-brain barrier (BBB)
during normal aging in the human hippocampus, a region involved in learning and …

… The role of the blood–brain barrier (BBB) breakdown has been recognized as being …
hormones with aging. Indeed, estrogen is known to have a neuroprotective effect through several …

… consequences of BBB breakdown by emphasizing the aging … breakdown associated with
normal aging that further cause … normal aging and neurodegenerative disorders such as AD. …

… of the BBB in the HC and PHG in APOE4 carriers, but not APOE3 homozygotes, remained a
highly significant predictor of cognitive impairment after we statistically controlled for age, sex…

… of the brain, known as the blood–brain barrier (BBB), is understood … an age-related shift in
transport from ligand-specific receptor-mediated to non-specific caveolar transcytosis. This age…

… Aging-induced alterations to the blood–brain barrier (BBB) … -1 in reducing BBB integrity
during aging and show altered … junction protein expression changes during aging as well as be …

… ELS may persistently and sex dependently influence blood–brain barrier (BBB) integrity
and … the majority of studied proteins related to BBB function in age‐, region‐ and sex‐dependent …

… The schematic diagram of the neurovascular unit and blood-brain barrier (BBB). The
neurovascular unit consists of pericytes, neurons, endothelial cells, clusters of glial cells, and the …

… Here, we evaluated the impact of BBB permeability, as measured by the widely applied CSF/…
, and imaging AD core biomarkers across the aging and AD spectrum. We hypothesize that …