… In this study, we explore whether the cognitive impairment in the diabetic rat is associated
with increased blood brain barrier (BBB) permeability and the change of the inflammatory …

… Lastly, it is possible that some part of the AGE-mediated effects result from the action of AGE
on pericytes, leading to indirect modulation of BMVEC through TGF-β. In vitro, a change in …

Purpose To investigate whether the blood-brain barrier (BBB) leaks blood-circulating substances
in patients with early forms of Alzheimer disease (AD), and if so, to examine the extent …

… Age-related blood-brain barrier (BBB) disruption and … of novel interventions to reverse
age-related alterations of the … of age-related increase in blood-brain barrier permeability and …

… these subsets in blood-brain barrier (BBB) breakdown by studying natural aging and simian
… and the percentage of type-2 pericytes regardless of age or SIV status. Taken together, our …

… Blood–brain barrier (BBB) dysfunction is considered to be an early event in the pathogenesis
of a variety of neurological diseases in old patients, and this could occur in old people …

… Therefore, among the most important consequences of Hch are damage to the cerebral
arterial walls and increased permeability of the blood-brain barrier (BBB). Vascular wall …

… In this narrative review, a theoretical framework on the crosstalk between physical exercise
and blood-brain barrier (BBB) permeability is presented. We discuss the influence of physical …

… of blood-brain barrier (BBB) is a major pathophysiological mechanism of postoperative
cognitive dysfunction (POCD) in the elderly. The reduced beneficial gut microbiome due to aging …

… (AD) is an age-related disease, with loss of integrity of the blood–brain barrier (BBB) being …
Cellular senescence is one of the reported nine hallmarks of aging. Here, we show for the first …