Dissociable roles for the ventral and dorsal medial prefrontal cortex in cue-guided risk/reward decision making

M van Holstein, SB Floresco - Neuropsychopharmacology, 2020 - nature.com
… of the medial prefrontal cortex (mPFC) corresponding to the anterior cingulate cortex (ACC),
in mediating different aspects of reward-related decisions involving uncertainty or risk. …

Distinct medial orbitofrontal–striatal circuits support dissociable component processes of risk/reward decision-making

NL Jenni, G Rutledge, SB Floresco - Journal of Neuroscience, 2022 - Soc Neuroscience
… The present findings reveal that both striatal regions depend on information processed by …
the specific cognitive/motivational processes subserved by the functional circuits it forms may …

Activation patterns of the dorsal medial prefrontal cortex and frontal pole predict individual differences in decision impulsivity

C Lv, Q Wang, C Chen, G Xue, Q He - Brain Imaging and Behavior, 2021 - Springer
… of the dorsal medial prefrontal cortex (DMPFC) and the frontal pole (FP) during the risk-taking
“… To this end, we scanned with functional magnetic resonance imaging (fMRI) techniques a …

The role of the medial prefrontal cortex in updating reward value and avoiding perseveration

CS Laskowski, RJ Williams, KM Martens… - Behavioural Brain …, 2016 - Elsevier
… that impaired functioning of the medial prefrontal cortex (mPFC… Bechara and colleagues
developed a risk-reward decision … partial dissociation of response flexibility and reward tracking. …

Contributions of medial prefrontal cortex to decision making involving risk of punishment

CA Orsini, SC Heshmati, TS Garman, SC Wall… - …, 2018 - Elsevier
… Thus, mPFC inactivation may have resulted in a dissociation of motivational value … differences
between male and female PFC function in risk taking behavior. A second limitation is that …

Differential impact of ventromedial prefrontal cortex damage on “hot” and “cold” decisions under risk

J Spaniol, F Di Muro, E Ciaramelli - Cognitive, Affective, & Behavioral …, 2019 - Springer
… (vmPFC) is known to play a key role in reward processing and … cortex and the ventral aspects
of the medial prefrontal … are chiefly responsible for producing dissociations such as the one …

Triple dissociation of attention and decision computations across prefrontal cortex

LT Hunt, WMN Malalasekera, AO de Berker… - Nature …, 2018 - nature.com
… In addition to providing functional dissociations across PFC subregions, our paradigm allowed
us to explore subjects’ information-sampling behavior, which suggested how the subjects …

Reward processing and circuit dysregulation in posttraumatic stress disorder

Y Lokshina, T Nickelsen, I Liberzon - Frontiers in psychiatry, 2021 - frontiersin.org
… components of reward functioning have been proposed, including reward wanting (or … ,
medial caudate and medial prefrontal cortex (mPFC) have been activated during anticipation of …

Prefrontal dopamine D1 and D2 receptors regulate dissociable aspects of decision making via distinct ventral striatal and amygdalar circuits

NL Jenni, JD Larkin, SB Floresco - Journal of Neuroscience, 2017 - Soc Neuroscience
… by these two receptors within the prefrontal cortex (PFC), with D … reward processing.
Specifically, PFC DA appears to mediate … dissociation of how PFC DA may modulate flexible …

Multifaceted contributions by different regions of the orbitofrontal and medial prefrontal cortex to probabilistic reversal learning

GL Dalton, NY Wang, AG Phillips… - Journal of …, 2016 - Soc Neuroscience
… Here we show that different regions of the orbitofrontal and medial prefrontal cortex make …
complex interplay between frontal lobe regions in mediating these processes and accordingly …