… by CYP3A4 in liver microsomes [11], [12]. Recent studies revealed the effect of CYP2C19 and CYP3A4geneticpolymorphisms on … The UKU sideeffect rating scale was designed to be …
… sideeffects did not differ significantly between carriers of polymorphic and wild-type CYP3A4*22 variants. In CYP3A4*22 carriers was observed trend towards significance in increase of …
VY Skryabin, MS Zastrozhin… - Journal of …, 2022 - journals.sagepub.com
… effect of CYP2C19 and CYP3A4geneticpolymorphisms on the pharmacokinetics of BZDs. The differences in the activity of these enzymes are genetically … undesirable sideeffects and …
DV Ivashchenko, OV Tereshchenko… - Neurology …, 2020 - nnp.ima-press.net
… оценки нежелательных эффектов (UKU SideEffect Rating Scale). … , CYP2D6 and ABCB1 genepolymorphisms and the safety of … и безопасность субстратов CYP3A4 [16]. Наи- …
C Belmonte, D Ochoa, M Román… - Basic & Clinical …, 2018 - Wiley Online Library
… The subjects were free to withdraw from the study at any time… that although it seems CYP3A4 enzyme plays an important … to evaluate the effect of geneticpolymorphisms on the response …
M Jose, J Mathaiyan, S Kattimani, S Adithan… - European journal of …, 2016 - Springer
… We studied the effect of CYP2C19 genepolymorphisms on … , at higher doses may lead to several sideeffects as it is a central … CYP3A4polymorphisms are less common in India and thus …
M Saiz-Rodríguez, S Almenara, M Navares-Gómez… - Biomedicines, 2020 - mdpi.com
… Subjects were free to withdraw from the study at any time. … Nevertheless, this study design allows the investigation of geneticpolymorphisms affecting PK while avoiding the influence of …
M Saiz‐Rodríguez, D Ochoa, C Herrador… - Basic & clinical …, 2019 - Wiley Online Library
… They were free to withdraw from the study at any time. The … is the first study to associate the CYP3A4*22 variant with the … can assess the effect of geneticpolymorphisms over fentanyl …
N Taşçıoğlu, Ç Saatçi, R Emekli, G Tuncel… - Turk. J. Clin …, 2021 - jag.journalagent.com
… to alcohol addicts to reduce withdrawalsymptoms may not have reached … studies about CYP3A4genepolymorphisms in the Turkish … should be made for drug sideeffects in our society. …