Genetic polymorphisms on OPRM1 Involved in multiple responses of a methadone maintenance population: Relationships with Insomnia, libido, smoking, and …

YL Liu, JH Tsung, CP Fang, SW Liu, CW Lai… - Neuropathology of Drug …, 2016 - Elsevier
… The opioid receptor, mu 1 (OPRM1) is a gene that encodes for the mu … discovered that the
genetic polymorphisms on the OPRM1 genetic regions were significantly associated with the …

Association of OPRK1 gene polymorphisms with opioid dependence in addicted men undergoing methadone treatment in an Iranian population

A Albonaim, H Fazel, A Sharafshah… - Journal of Addictive …, 2017 - Taylor & Francis
… association of opioid receptors genes with addiction … increase libido or sleep (like most
psychotropic drugs); (6) lack of psychotic problems (since many psychotic problems induce libido

Association of OPRD1 gene variants with opioid dependence in addicted male individuals undergoing methadone treatment in the north of Iran

A Sharafshah, H Fazel, A Albonaim… - Journal of …, 2017 - Taylor & Francis
… of OPRD1 gene variants with opioid dependence and libido … δ‐opioid receptor gene
polymorphisms in methamphetamine … of Medical Genetics Part B: Neuropsychiatric Genetics 141 (5…

Haplotype-Based Association and In Silico Studies of OPRM1 Gene Variants with Susceptibility to Opioid Dependence Among Addicted Iranians Undergoing …

HF Tolami, A Sharafshah, LF Tolami… - Journal of Molecular …, 2020 - Springer
… of these variants were associated with libido dysfunction or insomnia … , single nucleotide
polymorphisms (SNPs) of several genes, … bind to Mu-type opioid receptor was performed by the …

Genetic polymorphisms in the opioid receptor delta 1 (OPRD1) gene are associated with methadone dose in methadone maintenance treatment for heroin …

CP Fang, SC Wang, HH Tsou, RH Chung… - … of Human Genetics, 2020 - nature.com
… Delta opioid receptor (DOR) is well known to be involved in heroin dependence. This …
polymorphisms (SNPs) in the opioid receptor delta 1 (OPRD1) gene coding region are associated

[HTML][HTML] Sleep quality and OPRM1 polymorphisms: a cross-sectional study among opioid-naive individuals

Z Zahari, MA Ibrahim, N Musa, SC Tan… - Brazilian Journal of …, 2018 - SciELO Brasil
Genetic polymorphisms in the opioid receptor mu1 gene are associated with changes in
libido and insomnia in methadone maintenance patients. Eur Neuropsychopharmacol. 2012;22(…

The impact of OPRM1's genetic polymorphisms on methadone maintenance treatment in opioid addicts: a systematic review

B Oueslati, O Moula, R Ghachem - Pharmacogenomics, 2018 - Future Medicine
opioid receptors or SNP or polymorphism or gene). Endpoint of the included studies had to
be the impact of OPRM1 gene polymorphisms on … and opioid receptor genetic polymorphisms

The AC/AG diplotype for the 118A> G and IVS2+ 691G> C polymorphisms of OPRM1 gene is associated with sleep quality among opioid-dependent patients on …

Z Zahari, CS Lee, MA Ibrahim, N Musa… - Pain and therapy, 2016 - Springer
opioid receptor mu 1 which is encoded by the OPRM1 gene. … sleep quality and opioid genetic
polymorphisms. Thus, in the … and side effects included changes in libido and insomnia [24]…

κ opioid receptor 1 single nucleotide polymorphisms were associated with the methadone dosage

Q Zhang, M Shi, H Tang, H Zhong… - Genetic Testing and …, 2020 - liebertpub.com
genetic polymorphisms were associated with the methadone dose used daily. Methadone is
a long-lasting mu-opioid receptor … The κ opioid receptor has anti-reward effects throughout …

Influence of DRD2 polymorphisms on the clinical outcomes of opioiddependent patients on methadone maintenance therapy

Z Zahari, CS Lee, MA Ibrahim, N Musa… - Journal of Pharmacy …, 2020 - journals.lww.com
polymorphisms on methadone treatment outcomes. There are however studies that investigated
the impact of genetic polymorphisms … CYP2B6),[ 10 ] opioid receptor mu 1 (OPRM1),[ 12 …