… testosterone associations measured in men; therefore, our findings are largely relevant to
common diseases in men. … region to genetically predict testosterone. SHBG can bind to free …

… separate-sample MR study design to assess the effect of endogenous peak testosterone on
cognitive function in older men… genetically predicted testosterone with systemic inflammation, …

… on causal effects of genetically predicted estradiol on systemic inflammation among women
… genetic predictors of testosterone with CVD and associated risk factors in men using genetic …

… old) with systemic inflammatory markers using a separate-sample Mendelian randomization
… and cancer, endogenous testosterone could predict these diseases. Inversely, excessive …

… Observationally, higher plasma cortisol to testosterone ratio has been found associated
with … Another MR showed genetically predicted cortisol based on two genetic instruments …

… approach to examine the role of testosterone and estrogen in … We used separate sample
instrumental variable analysis to … SS Cherny, MM Garcia-Barcelo, SO Man, L Xu, and T Zhu for …

… It is assumed that there is no direct path between the genetic … The causal estimates were in
the expected direction with lower … no significant association between testosterone [22] or 17β-…

… While this has improved our understanding of the genetic basis … We also found the negative
effects of PC3 on testosterone … Using the GIANT consortium as a separate sample 25 , we …

… cardiovascular disease rates than men, and the menopause … used a separate sample
Mendelian randomization analysis … genetically predicted estrogen was unrelated to testosterone …

… (OR 2·93, 1·27 to 6·73) in men, but not women (OR for MI 0·80, 95% CI 0·… genetically predicted
insulin with MI, angina, heart failure, and cardiovascular risk factors from separate sample …