Autonomous vehicles are artificial intelligence-based mobility devices. They are not a new technological development as the concept has been a work-in-progress for centuries. However, this century has the unique opportunity to witness the emergence of self-driving cars on roads all over the world. This, thus, makes it imperative to quickly address how the world would change with robotaxis on our roads and how we ought to prepare for them. The advantages and disadvantages of autonomous driving machines abound; however, the onus is on governments to minimize the threats and harness the benefits. This chapter, therefore, is about how governments can effectively leverage autonomous vehicles to promote humans' quality of life and the necessary considerations on how to minimize the risks associated with self-driving vehicles.