KB Hanscombe, DL Morris, JA Noble… - Human molecular …, 2018 - academic.oup.com
… including HLA-DRB1 * 15:02 in LD with DQA1 * 01 and … as the three HLA alleles share the same amino acid residue … in the MHC in an AA and EUR population have identified the key …
NV Rivera, M Ronninger, K Shchetynsky… - American journal of …, 2016 - atsjournals.org
… A shared overlap between LS and non-LS defined by 17 … a range of autoimmune and inflammatory diseases (8–11) but … Additionally, because HLA-DRB1*03 plays a strong role in the …
… by a combination of inflammatory and degenerative changes … there were shared amino acid positions within HLA–DRB1 risk … High-density genetic mappingidentifies new susceptibility …
R Busch, S Kollnberger, ED Mellins - Nature Reviews Rheumatology, 2019 - nature.com
… The advent of high-density single-nucleotide polymorphism (… SE of HLA-DRB1 in disease susceptibility and identified an … The SpAs share associations of varying strength (greatest for …
CT Deakin, J Bowes, LG Rider, FW Miller… - Human molecular …, 2022 - academic.oup.com
… the most common idiopathic inflammatory myopathy of children. … AH8.1 and HLA-DRB1 * 03:01, HLA-C * 02:02 and identify a … While JDM and adult-onset dermatomyositis (DM) share …
F Degenhardt, G Mayr, M Wendorff… - Human molecular …, 2021 - academic.oup.com
… Inflammatory bowel disease (IBD) is a chronic inflammatory … Notably, we identified DRB1 * 01:03, which was identified as … In the analysis of peptide-binding preferences for HLA-DRB1 …
… region has been improved by highdensity array-based … peanut allergy and HLA-DRB1*08 and DQB1*06:03 alleles 24. … s) found at sites of inflammation in AS to cytotoxic T lymphocytes…
… The HLA-DRB1*03:01 allele is a … identified SLE-relevant terms that were shared between 65-79*LE-treated human and mouse macrophages, including terms pertaining to inflammatory …
S Rothwell, RG Cooper, IE Lundberg… - Annals of the …, 2016 - ard.bmj.com
… were identified. HLA imputation confirmed that alleles HLA-DRB1*03:01 and HLA-B*08:01 … While there is evidence that risk loci may be shared across populations, such as STAT4 and …