… Human cytomegalovirus (HCMV) contributes significantly to morbidity and mortality in
immunocompromised patients, especially after transplantation, as well as in congenitally infected …

… HCMV-specific target enrichment and high-throughput … with human cytomegalovirus (HCMV;
species Human … family Herpesviridae, are highly prevalent in people worldwide and result …

… ) and thus to analyse the extent of HCMV genome diversity and its potential impact on clinical
… Similarly, extensive HCMV strain variability among different individuals with high intrahost …

… we review recent studies that have used high-throughput … genetic diversity found among the
members of each species of … a new genotype to become prevalent, akin to a genetic shift. (B) …

… These results highlight that high HCMV diversity present in some samples is caused by …
the host diversity for single-strain HCMV infections is no greater than for other herpesviruses. …

… In this review, an overview of HCMV next-generation … in genomic diversity, strain genotyping,
full-length genome methodologies… High-throughput NGS allowed to increase the number of …

… Human cytomegalovirus (HCMV) poses a risk, particularly to … with human immunodeficiency
virus/AIDS. Prior to the advent of high-throughput technologies, studies of HCMV genomes …

… We highlight examples of where our approach can help to provide insights for further …
To characterize CMV genomic diversity, we first aligned the genomes and then calculated …

… Strain diversity was extensive among individuals but … High-throughput sequencing studies
at the whole-genome level have started to facilitate a broader view of HCMV diversity, but …

… HCMV genomics has been significantly advanced in recent years by high-throughput …
variation among HCMV strains, had previously required extensive manual intervention. The variant …