Thyroid hormone-regulated chromatin landscape and transcriptional sensitivity of the pituitary gland

YW Cho, Y Fu, CCJ Huang, X Wu, L Ng… - Communications …, 2023 - nature.com
hormone receptor β (TRβ) and analyze T3-regulated open chromatin using an anterior
pituitary-specific … (DR4), resembling T3 receptor binding motifs first identified in vitro in the Gh and …

A direct comparison of thyroid hormone receptor protein levels in mice provides unexpected insights into thyroid hormone action

S Minakhina, S Bansal, A Zhang, M Brotherton… - Thyroid, 2020 - liebertpub.com
… We acknowledge that detection of THR protein may vary from organ to organ. This could
explain our failure to detect THRB1 in the heart, muscle, iWAT, and some neural tissues, …

[HTML][HTML] Physiology of the hypothalamic-pituitary-thyroid axis

S Mariotti, P Beck-Peccoz - Endotext [Internet], 2021 - ncbi.nlm.nih.gov
… 5, T3 acts via binding to the nuclear thyroid hormone receptor β2 … conditions of difficult
identification and diagnosis. … consensus sequence for the pituitary-specific transcription factor Pit-1 …

Thyroid-stimulating hormone

VD Sarapura, MH Samuel - The pituitary, 2017 - Elsevier
… for determination of the cells that produce the glycoprotein … binding sites for the pituitary-specific
transcription factor, Pou1F1… for retinoid receptors and thyroid hormone receptors (SMRTs…

Thyroid-Stimulating Hormone

L Chaker, RP Peeters - The Pituitary, 2022 - Elsevier
identified to date [126]. Monocarboxylate transporter 8 (MCT8) is the most specific thyroid
hormone transporter identified, … is initiated by T3 binding to thyroid hormone receptors (TR), …

Pituitary NR4A1 is negatively regulated by thyroid hormone without direct binding of thyroid hormone receptors on the gene

T Okamura, Y Nakajima, N Shibusawa… - Molecular and Cellular …, 2018 - Elsevier
… gene in conjunction with the pituitary-specific transcription factor, Pit1, and the hematopoietic
transcription factor, GATA2, which have previously been identified as important factors for …

Detection and localization of the thyroid hormone receptor beta mRNA in the immature olfactory receptor neurons of chum salmon

H Kudo, A Eto, T Abe, K Mochida - Heliyon, 2018 - cell.com
… However, thyroid hormone receptor (TR) expression in the … receptor neurons (ORNs), as
protein gene product 9.5 (PGP9.5)-immunopositive ORNs. Our results provide the first detection

Thyroid hormone receptor α1: a novel regulator of thyroid cancer cell differentiation

E Hwang, WKL Doolittle, YJ Zhu, X Zhu, L Zhao, Y Yu… - Oncogene, 2023 - nature.com
… The present studies identified one mechanism by which TRα1 acted to re-differentiate ATC.
Thus, TRα1 is a newly identified regulator of thyroid differentiation. Our findings could have …

Is it time to consider the expression of specific-pituitary hormone genes when typifying pituitary tumours?

A García-Martínez, J Sottile, C Fajardo, P Riesgo… - PLoS …, 2018 - journals.plos.org
… of pituitary hormones and their pituitary-specificpituitary-specific transcription factors,
detecting the dominant expression of the pituitary-specific hormone genes allowed us to identify

Comprehensive map and functional annotation of human pituitary and thyroid proteome

X Liu, Z Guo, H Sun, W Li, W Sun - Journal of Proteome Research, 2017 - ACS Publications
… We identified the right lobe and left lobe of the thyroid glandfunction comparison of
pituitary-specific proteins and thyroid-… Protein–protein interaction networks were identified as …