[HTML][HTML] Phenome and genome based studies into human ageing and longevity: An overview
… The molecular basis for human longevity has not … genetic component in human longevity
and the phenotypic definitions and approaches used in studies to identify genetic determinants. …
and the phenotypic definitions and approaches used in studies to identify genetic determinants. …
[HTML][HTML] Current Trends and Approaches to the Search for Genetic Determinants of Aging and Longevity
SS Kunizheva, VP Volobaev, MY Plotnikova… - Russian Journal of …, 2022 - Springer
… of human aging and longevity: the study of individual candidate genes in genetic population
studies, variations identified by … in aging, and genomic studies to identify factors of “healthy …
studies, variations identified by … in aging, and genomic studies to identify factors of “healthy …
[HTML][HTML] How important are genes to achieve longevity?
C Caruso, ME Ligotti, G Accardi, A Aiello… - International Journal of …, 2022 - mdpi.com
… genetic determinants of longevity are dynamic and depend on the environmental history of
a given population… While linkage analysis was successfully used to identify genetic variants …
a given population… While linkage analysis was successfully used to identify genetic variants …
[HTML][HTML] Human longevity: Genetics or Lifestyle? It takes two to tango
… has led to the identification of genes correlated with the maintenance of the cell and of its …
genetic factors affecting the individual variation of the aging phenotype. In addition, studies on …
genetic factors affecting the individual variation of the aging phenotype. In addition, studies on …
How the effects of aging and stresses of life are integrated in mortality rates: insights for genetic studies of human health and longevity
… These include studying roles of genetic factors in human aging and longevity, identifying …
additional opportunity for studying how genetic factors associated with lifespan influence age …
additional opportunity for studying how genetic factors associated with lifespan influence age …
[HTML][HTML] Employing biomarkers of healthy ageing for leveraging genetic studies into human longevity
… longevity. We identified several genetic variants influencing the variation in glucose, insulin
and … Hence, we will apply the same approach to identify loci contributing to human longevity. …
and … Hence, we will apply the same approach to identify loci contributing to human longevity. …
Human ageing genomic resources: new and updated databases
R Tacutu, D Thornton, E Johnson… - … acids research, 2018 - academic.oup.com
… database of human genetic association studies of longevity with >… human genes database
identified a robust group of ageing-… studies, thus enabling researchers to study what factors …
identified a robust group of ageing-… studies, thus enabling researchers to study what factors …
Biology of healthy aging and longevity
JJ Carmona, S Michan - Revista de investigacion clinica, 2016 - medigraphic.com
… It also has allowed identifying circulating aging/pro-aging factors such as the growth
differentiation factor 11 (GDF11) that acts in muscle and the cytokine CCL11 in the brain10-12. …
differentiation factor 11 (GDF11) that acts in muscle and the cytokine CCL11 in the brain10-12. …
The genetics of human ageing
… genome-wide association studies have recently identified many loci that influence key human
ageing traits, including lifespan… the genetic factors driving this variability in ageing between …
ageing traits, including lifespan… the genetic factors driving this variability in ageing between …