Age-and gender-dependent D-amino acid oxidase activity in mouse brain and peripheral tissues: implication for aging and neurodegeneration

SH Kim, Y Shishido, H Sogabe… - The journal of …, 2019 - academic.oup.com
D-amino acid oxidase (DAO) is a flavoenzyme that catalyses oxidative deamination of D-amino
acids to the corresponding imino acids … in schizophrenia: immunohistochemical and in …

[HTML][HTML] Novel insights into renal d-amino acid oxidase accumulation: propiverine changes DAAO localization and peroxisomal size in vivo

L Luks, S Sacchi, L Pollegioni, DR Dietrich - Archives of toxicology, 2017 - Springer
… epithelial cells in rats. Previously, the accumulating protein was identified as d-amino acid
oxidase (DAAO), a peroxisomal flavoenzyme expressed in kidney, liver and brain. The cellular …

[HTML][HTML] … of D-Amino Acid Oxidase (DAO/DAAO) and D-Amino Acid Oxidase Activator (DAOA/G72) during Development and Aging in the Human Post-mortem Brain

V Jagannath, Z Marinova, CM Monoranu… - Frontiers in …, 2017 - frontiersin.org
D-amino acid oxidase (DAO/DAAO; from now on addressed as DAO) is a flavoenzyme, which
oxidizes D-amino acids. … Immunohistochemical studies measured DAO immunoreactivity in …

d-Amino Acid Oxidase and d-Aspartate Oxidase

Y Kato, DH Tran, HTT Trinh, K Fukui - D-Amino Acids: Physiology …, 2016 - Springer
… a coenzyme, and localizes in peroxisomes in the cells of kidney, liver and brain. Since DAO
was … Upper panels display the results of immunohistochemical analysis of the human choroid …

[HTML][HTML] Mouse d-Amino-Acid Oxidase: Distribution and Physiological Substrates

R Koga, Y Miyoshi, H Sakaue, K Hamase… - Frontiers in molecular …, 2017 - frontiersin.org
… various D-amino acids, many D-amino acids accumulate in the tissues and body fluids of the
mutant mice. These amino acids … D-serine levels in the plasma and brain. Among the above …

[HTML][HTML] Blood levels of D-amino acid oxidase vs. D-amino acids in reflecting cognitive aging

CH Lin, HT Yang, CC Chiu, HY Lane - Scientific reports, 2017 - nature.com
D-amino acid oxidase (DAO) and amino acids can regulate … peripheral DAO and amino
acids levels are characteristic of … in brain tumor cells expressing Rhodotorula gracilis D-amino

[HTML][HTML] Human D-amino acid oxidase: structure, function, and regulation

L Pollegioni, S Sacchi, G Murtas - Frontiers in Molecular Biosciences, 2018 - frontiersin.org
… levels of D-amino acids were barely detectable and their presence in many tissues was
questioned. Later on, appreciable levels of various D-amino acids were determined in brain and …

Generation of specific antisera directed against D-amino acids: focus on the neuroanatomical distribution of D-glutamate and other D-amino acids

R Coveñas, A Mangas, ML Sánchez… - Folia Histochemica …, 2017 - journals.viamedica.pl
… for D-glutamate in the rat brain, this D-amino acid could be involved for example in auditive,
… By using immunohistochemical techniques D-amino acids can be readily visualized, and …

[HTML][HTML] Biochemical properties of human D-amino acid oxidase variants and their potential significance in pathologies

S Sacchi, P Cappelletti, G Murtas - Frontiers in molecular biosciences, 2018 - frontiersin.org
D-amino acid oxidase (DAAO) catalyzes the oxidative deamination of neutral and polar D-amino
acids producing the corresponding α-keto acids, … from D-amino acid detoxification in …

Converging Evidence on D-Amino Acid Oxidase–Dependent Enhancement of Hippocampal Firing Activity and Passive Avoidance Learning in Rats

LV Nagy, ZK Bali, G Kapus, P Pelsőczi… - International Journal …, 2021 - academic.oup.com
… mechanisms limiting the brain concentration of D-serine is the D-amino acid oxidase (DAAO…
the mammalian brain, it has been confirmed with in situ hybridization that DAAO, both in rats