A novel pathway for the production of H2S by DAO in rat jejunum

S Tang, D Huang, N An, D Chen… - Neurogastroenterology …, 2016 - Wiley Online Library
… by Western blotting and immunohistochemistry. The short-circuit … of H 2 S by D-Amino
acid oxidase (DAO) in rat jejunum. D-… whether H 2 S was generated from DAO in rat jejunum. …

Intramuscular Delivery of scAAV9-hIGF1 Prolongs Survival in the hSOD1G93A ALS Mouse Model via Upregulation of D-Amino Acid Oxidase

HQ Lin, HJ Hu, WS Duan, YL Liu, GJ Tan, ZY Li… - Molecular …, 2018 - Springer
… In addition, scAAV9-hIGF1 protected motor neurons from apoptosis through upregulation of
D-amino acid oxidase (DAO), which controls the level of D-serine. Moreover, to further verify …

D-Serine made by serine racemase in Drosophila intestine plays a physiological role in sleep

X Dai, E Zhou, W Yang, X Zhang, W Zhang… - Nature …, 2019 - nature.com
… to be the only natural form, D-amino acids have been found in … measurement 9 and
immunohistochemistry 10 supports D-Ser … We found that all five lines were expressed in the brain, …

Proline oxidase controls proline, glutamate, and glutamine cellular concentrations in a U87 glioblastoma cell line

P Cappelletti, E Tallarita, V Rabattoni… - PLoS …, 2018 - journals.plos.org
… in this study to investigate PO localization and function since it … the human flavoenzyme
D-amino acid oxidase and to investigate … Immunohistochemical localization of GLAST and GLT-1 …

ASCT1 (Slc1a4) transporter is a physiologic regulator of brain d-serine and neurodevelopment

E Kaplan, S Zubedat, I Radzishevsky… - Proceedings of the …, 2018 - National Acad Sciences
… To determine the localizations of ASCT1, we carried out immunohistochemistry using
ASCT1-KO mice as negative controls to ensure antibody specificity. We found that ASCT1 …

D-Serine Metabolism and Its Importance in Development of Dictyostelium discoideum

T Ito, N Hamauchi, T Hagi, N Morohashi… - Frontiers in …, 2018 - frontiersin.org
… δ2 glutamate receptors, and is involved in brain functions such as learning and memory. …
with various D-amino acids. Purified DAO was incubated with 10 mM of D-amino acid and the …

Mammalian D‐cysteine: A novel regulator of neural progenitor cell proliferation: Endogenous D‐cysteine, the stereoisomer with rapid spontaneous in vitro …

R Roychaudhuri, SH Snyder - Bioessays, 2022 - Wiley Online Library
… , and D-tyrosine in rat brains by immunohistochemistry. They detected D-glutamate in the …
on D-amino acids was also shown by Suzuki et al. [ 43 ] This study showed that D-amino acid

Biochemical properties and physiological functions of pLG72: twenty years of investigations

G Murtas, L Pollegioni, G Molla, S Sacchi - Biomolecules, 2022 - mdpi.com
… its ability to bind and inactivate the flavoenzyme d-amino acid oxidase, ie, the enzyme that
… in the brain. pLG72 was proposed to target the cytosolic form of d-amino acid oxidase for …

Alteration in plasma and striatal levels of D-serine after D-serine administration with or without nicergoline: An in vivo microdialysis study

M Onozato, H Nakazawa, K Ishimaru, C Nagashima… - Heliyon, 2017 - cell.com
… Potential pathophysiological role of d-amino acid oxidase in schizophrenia:
immunohistochemical and in situ hybridization study of the expression in human and rat brain. …

Structural basis for potent inhibition of d-amino acid oxidase by thiophene carboxylic acids

Y Kato, N Hin, N Maita, AG Thomas, S Kurosawa… - European Journal of …, 2018 - Elsevier
… catalyzes the oxidation of d-amino acids, producing the corresponding α-keto acids, ammonia,
and hydrogen peroxide [1]. One of the endogenous substrates for DAO in the brain is the …