C Stillhart, K Vučićević, P Augustijns, AW Basit… - … of Pharmaceutical …, 2020 - Elsevier
… The release and absorption profile of an oral medication is influenced by the physicochemical properties of the drug and its formulation, as well as by the anatomy and physiology of the …
MK Parr, O Montacir, H Montacir - … pharmaceutical and biomedical analysis, 2016 - Elsevier
… strongly impact the final biological. Thus, quality assurance of biopharmaceuticals results in … The molecular weight of the intact molecule is the first physical parameter to be analyzed …
R Joubert, JD Steyn, HJ Heystek… - Expert opinion on …, 2017 - Taylor & Francis
… of a generic product depending on the biopharmaceutical classification of the specific drug. However, … Furthermore, these physiologicalfactors that can affect drug absorption from the …
… The absorption of oral drugs is frequently plagued by significant variability with … consequences. The source of variability can be traced back to interindividual variability in physiology, …
P Macheras, P Chryssafidis - Pharmaceutical research, 2020 - Springer
… on physiological aspects of the gastrointestinal (GI) tract [6] such as (a) drug/formulation-dependent factors— drug physicochemical … no first pass effect, ie fraction of dose absorbed = …
F Wu, H Shah, M Li, P Duan, P Zhao, S Suarez… - The AAPS Journal, 2021 - Springer
… biopharmaceutics applications) integrates gastrointestinal (GI) tract anatomical and physiological aspects with drug physicochemical … of effect of elevating pH on the oral absorption of …
M Ashford - Aulton's Pharmaceutics E-Book: The Design and …, 2017 - books.google.com
… drug absorption. … effect of physicochemical and dosage form factors such as the influence of salts and particle size on the predicted plasma profile and the effect of physiologicalfactors …
PC Acharya, C Fernandes, S Mallik, B Mishra… - Dosage form design …, 2018 - Elsevier
… the physicochemical, physiological, and pharmaceuticalfactors to … This chapter focuses on various physiological constraints … the physiological barriers that can affect the drug absorption …
P Zarmpi, T Flanagan, E Meehan, J Mann, N Fotaki - The AAPS Journal, 2020 - Springer
… affect the biopharmaceutical profile of drugs with potential implications on drug absorption (2,3… of excipient in the total volume of the physical mixture as per the poorly soluble drugs. The …