… In Conclusion, dual activation of PPAR-γ and PPAR-α has … fatty liver disease (NAFLD) is
a cluster of liver disorders … liver index percent with a decrease in body weight compared to …

… Three PPAR isoforms have been identified, PPARα, β/δ and … role of spexin in reducing blood
pressure and hyperuricaemia… the vasculature including endothelial impairment and loss of …

… enzyme activities and up-regulated PPARα expression, while … element expression to
modulate hepatic disorders [35]. The … on hepatic PPARα gene expression and a decrease effect …

… weight of rats, which may be attributed to the ability of fructose to … The impairment of the
insulin signal and insulin resistance … by a significant decrease in the hepatic expression of IRS-2. …

… RESULTS: Rats fed FED showed damaged liver, impairment of … resulted from a reduction
in the hepatic catabolism of fatty … PPARα agonists as fenofibrate inhibits the development of …

… Mice fed with 30%fructose in water developed hepatic … peroxisome proliferators-activated
receptor α (PPARα) which in … steatosis (as evidenced by decreased NASH activity score, and …

… fructose consumption led to a significant decrease of PPARα … we suggest that the hepatic
PPARα activation in these animals … timing of hepatic mitochondrial dysfunction and lipogenesis …

… liver inflammation and lipid accumulation in fructose-fed rats with metabolic syndrome. It also
suppressed hepatic inflammatory signaling activation by reducing … -1 activity, which in turn …

… While fibrates are used to treat disorders other than the … The STAT3 pathway was activated
in adipose and hepatic tissues in … mice treated with 30% fructose, when the JAK2/STAT3 was …

… and liver TAG levels in fructose-fed rats were reduced with … study, fructose feeding caused
up-regulation of hepatic ACLY … Treatment with curcumin significantly reduced hepatic …