… clustered on chromosome 4, we demonstrate that NF-κB … genes, whereas c-Jun has
little effect. Together, our results uncover AP-1 as an important determinant for inflammation-induced …

… 209 and 45 genes whose E2-mediated upregulation or downregulation was enhanced by …
Although the mechanism for the opposite roles of TGFBI as regards induction of resistance is …

… in AP-1 regulation, as osmotic stress downregulates c-JUN via the … of a dominant negative
IκB results in decreased nuclear NF-κB … with NF-κB, activates AP-1, inducing the expression of …

… with gingipain-induced COX-2 expression. To clarify the transcription factors regulated by
ERK1/2 in gingipain-induced COX-2 expression, we examined the level of expression and …

… or a negative … C-Jun generally promotes cell proliferation through induction of CCND1 (cyclin
D1) and inhibition of p16 and p21 [14]. JunB usually inhibits cell proliferation via induction …

… that apoE gene expression in macrophages is downregulated through a … of this dominant
negative mutant (c-Jun DN), lacking a major part of the transactivation domain, had induced …

… of the AP-1 pathway and its contribution to HTLV-induced … of c-Jun by ERK on one serine
located next to the C-terminal … inhibits c-Jun DNA-binding activity, phosphorylation of Fra-1 and …

… with c-Jun increases c-Fos nuclear retention inhibits nuclear exit, … AP-1 and NF-κB dual
inhibitor SP100030 is one of the first reported small molecules to inhibit gene expression induced …

… of overlapping genes (93/103 of the genes upregulated in … of the genes downregulated in
TamR cells) harbored an AP-1 … therapy, we induced the expression of the DN-cJun at a later …

… , we examined the effect of apigenin on c-jun and c-fos by performing Western blotting …
downregulation of AP-1 activity. We found that apigenin did not affect c-jun and c-fos expression …