Proteomics and metabolomics in ageing research: from biomarkers to systems biology

JM Hoffman, Y Lyu, SD Pletcher… - Essays in …, 2017 - portlandpress.com
… of the biological processes that influence ageing and … need for integrating networks of
multiple ‘omicsdata types to … levels of omics data that can be applied to ageing and ageing-…

Omics sciences for systems biology in Alzheimer's disease: State-of-the-art of the evidence

H Hampel, R Nisticò, NT Seyfried, AI Levey… - Ageing Research …, 2021 - Elsevier
… This review summarizes the state-of-the-art of omics biomarker signatures in AD, including
… on the integration of neuroimaging and omics data, as well as how the evolving multi-omics

Integrated multi-omics for novel aging biomarkers and antiaging targets

L Wu, X Xie, T Liang, J Ma, L Yang, J Yang, L Li, Y Xi… - Biomolecules, 2021 - mdpi.com
… recent studies in the field of aging based on different multi-omics … We integrate aging
biomarkers of different omics levels to … analysis of different omics data, and systems biology have …

Measuring biological age using omics data

J Rutledge, H Oh, T Wyss-Coray - Nature Reviews Genetics, 2022 - nature.com
omics data into composite ageing biomarkers that help interpret the complex biology of
ageing … (bottom), which attempt to integrate the entire breadth of molecular changes that occur …

Promising biomarkers of human aging: In search of a multi-omics panel to understand the aging process from a multidimensional perspective

NA Rivero-Segura, OY Bello-Chavolla… - Ageing research …, 2020 - Elsevier
… Approaches which integrate findings from systems biology and translational studies have
resulted in the characterization of different biomolecules, obtained from tissue samples at …

[图书][B] Integration of omics approaches and systems biology for clinical applications

A Vlahou, F Magni, H Mischak, J Zoidakis - 2018 - books.google.com
… a rapidly aging population. The book presents novel insights on CKD and bladder cancer
obtained by omics data integration as an example of the application of systems biology in the …

Emerging omics approaches in aging research

JS Lorusso, OA Sviderskiy… - Antioxidants & redox …, 2018 - liebertpub.com
Systems biology approaches in aging research. (A) … underlie aging requires integration of
multi-layered data about age-… of reliable biomarkers to predict biological age. Importantly, by …

Network approaches to systems biology analysis of complex disease: integrative methods for multi-omics data

J Yan, SL Risacher, L Shen… - Briefings in bioinformatics, 2018 - academic.oup.com
… so that biologically meaningful biomarkers can be identified. … the multi-omics data into an
integrated framework as none of the … for full interpretation of a biological system [99]. Particularly …

Aging biomarkers: from functional tests to multi‐omics approaches

KS Kudryashova, K Burka, AY Kulaga… - …, 2020 - Wiley Online Library
… summarize data on all existing groups of biomarkers and biomarker-based age predictors
(… The next logical step is the integration of single omics data into one network. Given the high …

Multi-omics approaches to human biological age estimation

I Solovev, M Shaposhnikov, A Moskalev - Mechanisms of Ageing and …, 2020 - Elsevier
… -omics data as aging biomarkers on integral approach will make the prediction of biological
age … nothing was reported on systems biology approaches in aging biomarker search and …