Long non-coding RNAs regulate drug resistance in cancer
Molecular cancer, 2020•Springer
Chemoresistance, whether intrinsic or acquired, is a major obstacle in the treatment of
cancer. The resistance of cancer cells to chemotherapeutic drugs can result from various
mechanisms. Over the last decade, it has been reported that 1ong noncoding RNAs
(lncRNAs) can mediate carcinogenesis and drug resistance/sensitivity in cancer cells. This
article reviews, in detail, recent studies regarding the roles of lncRNAs in mediating drug
resistance.
cancer. The resistance of cancer cells to chemotherapeutic drugs can result from various
mechanisms. Over the last decade, it has been reported that 1ong noncoding RNAs
(lncRNAs) can mediate carcinogenesis and drug resistance/sensitivity in cancer cells. This
article reviews, in detail, recent studies regarding the roles of lncRNAs in mediating drug
resistance.
Abstract
Chemoresistance, whether intrinsic or acquired, is a major obstacle in the treatment of cancer. The resistance of cancer cells to chemotherapeutic drugs can result from various mechanisms. Over the last decade, it has been reported that 1ong noncoding RNAs (lncRNAs) can mediate carcinogenesis and drug resistance/sensitivity in cancer cells. This article reviews, in detail, recent studies regarding the roles of lncRNAs in mediating drug resistance.
Springer
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