… of IL-1β on intestinal TJ barrier, the intracellular mechanisms … signaling pathways
involved in TJ barrier modulation, the … shown that p38 kinase activation is required for IL-1β-induced …

… IL-1β-induced activation of p38 MAPK in IECs and subsequent increase in expression of
myosin light chain kinase involved … study was to delineate the underlying mechanisms. The data …

… The physical intestinal barrier consists of a continuous single … , cytokines modulate a wide
array of other intestinal epithelial … the intestinal epithelium of rhesus macaques induced IL-1β …

… Modulating PBLD expression may provide a novel approach for … Intestinal barrier dysfunction
in UC includes decreased … (IL-1β, IL-6, and IL-8) and enhanced NF-κB activation compared …

… it is involved in modulating protein metabolism, reproduction, … The levels of IL-6, IL-8, IL-1β,
and TNF-α were quantified by … on modulating p38 and ERK1/2 of the MAPK inflammatory …

… to what we previously described with IL-1β where the canonical pathway of NF-κB and …
-α–induced activation of p38 kinase is regulated by NIK, but p38 kinase is not involved in TNF-α–…

… blocking and activating the p38 MAPKs signaling pathway. … Challenge with ETEC K88
increased the gene expression of IL-1β, … hand, the p38 signaling pathway is directly involved in the …

… of proinflammatory cytokines including TNF-α, IL-1β, and IL-6, and … p38 MAPK pathway is
found to be involved in MLCK-… the intestinal I/R injury characterized by modulating p38 MAPK, …

… , IL-8, and IL-1β, and inhibited activation of nuclear factor κB (NF… 2C), but p38 activation was
not observed (data not shown). … NF-κB activation by pharmacological modulation could have …

… The loss of intestinal epithelial barrier function is an important … kinase pathway involved in
MMP-9 modulation of intestinal … IL-1β, target the MLCK gene activation to drive the increase in …