… metformin. We conclude that despite data in support of anti-aging benefits, the evidence that
metformin increases lifespan … cancer, metformin can improve healthspan thereby extending …

… Metformin, Survival and Longevity There is mounting evidence suggesting that metformin
increases lifespan and healthspan in model organisms such as worms [96,97,98,99] and mice […

… The results indicate that intermittent metformin treatment did not lead to early mortality and
that EOW metformin improves some metabolic markers of health without promoting lifespan …

… mass and extends survival of male mice on standard diet (SD) (6). SRT1720, another SIRT1
activator, improves healthspan and increases survival of middle-aged mice on SD (7) and …

… of healthspan, we believe that it is also critical to evaluate the efficacy of metformin to extend
healthspan … clinical trial is to identify if metformin can improve hallmarks of healthy aging in …

… Here we report on the impact of metformin on longevity and old age mobility … metformin
increases the median lifespan of all tested C. elegans strains, but not the median lifespan …

… The antidiabetic drug metformin exerts pleiotropic effects on multiple organs, including the
… that metformin improves healthspan and lifespan in male mice, yet its lifespan lengthening …

… Metformin, a biguanide that combats age-related disorders and improves health span, is the
first … in the large clinical trial—TAME (targeting aging by metformin). This review focuses on …

… In summary, this publication concluded that the lifespan extension with metformin that was …
Taken together, there is no evidence that metformin increases the lifespan of Drosophila, but it …

… revealed that metformin improved motor … that metformin improves cognitive skills with
decreased SA-β-gal activity and neurodegeneration in brain of the aged fish. Meanwhile, metformin …