Objectives Esophagogastroduodenoscopy (EGD) is considered a very effective method to
identify gastric cancer (GC). However, the existence of missed lesions has been frequently
discussed. This systematic review and meta-analysis aimed at assessing the magnitude of
missing GC diagnosis with EGD and its predictive factors. Methods MEDLINE was searched
to identify all studies assessing and reporting the proportion of missed GC diagnosis with
EGD. Pooled proportion and negative predictive values were computed using the random …