Δ-9-Tetrahydrocannabinol and Cannabidiol produce dissociable effects on prefrontal cortical executive function and regulation of affective behaviors

HJ Szkudlarek, SJ Desai, J Renard, B Pereira… - …, 2019 - nature.com
… Given the known role of PFC cannabinoid signaling in the … intra-PFC THC or CBD may
modulate set-shifting (see Methods… ) used in human research for testing frontal executive function […

[HTML][HTML] Task-independent acute effects of delta-9-tetrahydrocannabinol on human brain function and its relationship with cannabinoid receptor gene expression: A …

B Gunasekera, C Davies, G Blest-Hopley… - Neuroscience & …, 2022 - Elsevier
… to placebo, on brain function in humans using PET, SPECT… modulated acutely by a single
dose of THC in humans. We hypothesised that a single dose of THC will modulate the function

Acute effects of∆ 9-tetrahydrocannabinol (THC) on resting state brain function and their modulation by COMT genotype

MG Bossong, HH van Hell, CD Schubart… - European …, 2019 - Elsevier
Modulation of mediotemporal and ventrostriatal function in humans by delta9-tetrahydrocannabinol:
a neural basis for the effects of cannabis sativa on learning and psychosis …

Modulation of acute effects of delta-9-tetrahydrocannabinol on psychotomimetic effects, cognition and brain function by previous cannabis exposure

M Colizzi, P McGuire, V Giampietro, S Williams… - European …, 2018 - Elsevier
… , (−)-trans-Δ9-tetrahydrocannabinol (∆9-THC), might be modulated by previous cannabis
exposure. … Modulation of mediotemporal and ventrostriatal function in humans by Delta9-…

Delta-9-tetrahydrocannabinol increases striatal glutamate levels in healthy individuals: implications for psychosis

M Colizzi, N Weltens, P McGuire, D Lythgoe… - Molecular …, 2020 - nature.com
modulation of striatal activation is related to the severity of acute psychotomimetic effects
induced by it in humans … : (3) previous cannabis exposure would modulate the acute effect of ∆9-…

The Yin and Yang of Cannabis: a systematic review of human neuroimaging evidence of the differential effects of Δ9-tetrahydrocannabinol and cannabidiol

B Gunasekera, C Davies, R Martin-Santos… - Biological Psychiatry …, 2021 - Elsevier
modulate function in brain regions implicated in psychosis in healthy individuals (3, 4, 5, 6,
7, 8, 9) and exacerbate them in people … the activation and connectivity of the medial temporal

[HTML][HTML] The impact of cannabidiol on human brain function: a systematic review

A Batalla, J Bos, A Postma, MG Bossong - Frontiers in pharmacology, 2021 - frontiersin.org
… Furthermore, CBD modulated brain activity and had opposite … CBD modulated resting limbic
activity in subjects with anxiety … This included modulation of functional networks relevant for …

Previous cannabis exposure modulates the acute effects of delta-9-tetrahydrocannabinol on attentional salience and fear processing.

M Colizzi, P McGuire, V Giampietro… - Experimental and …, 2018 - psycnet.apa.org
… -Δ9-tetrahydrocannabinol (Δ9-THC), may be modulated by … modest previous cannabis
exposure modulated the acute effects … are more marked in people who have never used cannabis. …

Characterizing the Cognitive and Emotional Effects of delta-9-Tetrahydrocannabinol in Distinct Hippocampal Sub-Regions

D Khan - 2018 - search.proquest.com
… strongly implicates a role for cannabinoid signaling in the ventral hippocampus, specifically
in the modulation of affective/… The mediotemporal brain region is often implicated in the …

A single dose of cannabidiol modulates medial temporal and striatal function during fear processing in people at clinical high risk for psychosis

C Davies, R Wilson, E Appiah-Kusi… - Translational …, 2020 - nature.com
… that a single dose of CBD modulates activation of the medial temporal cortex and striatum
during fear processing in CHR patients. In showing that CBD modulates function of the neural …