Parvovirus capsid structures required for infection: mutations controlling receptor recognition and protease cleavages

HM Callaway, KH Feng, DW Lee, AB Allison… - Journal of …, 2017 - Am Soc Microbiol
… examine capsid substitutions that eliminate canine parvovirusAmino acid substitutions on
the exterior surface of the capsid (… Many parvovirus capsid structures have been determined to …

Single mutations in the VP2 300 loop region of the three-fold spike of the carnivore parvovirus capsid can determine host range

AB Allison, LJ Organtini, S Zhang… - Journal of …, 2016 - Am Soc Microbiol
… hosts in the evolution of canine parvovirus (CPV), a pandemic pathogen of domestic …
Many of these alternate amino acid residues are associated with different carnivore species, …

The Structures and Functions of Parvovirus Capsids and Missing Pieces: the Viral DNA and Its Packaging, Asymmetrical Features, Nonprotein Components, and …

RA López-Astacio, OF Adu, H Lee… - Journal of …, 2023 - Am Soc Microbiol
structure of the canine parvovirus (CPV) capsid revealed a 26-nm-diameter T=1 particle made
up of two … The amino acid sequence alignment of the NS1 proteins of mink enteritis virus (…

Complex and dynamic interactions between parvovirus capsids, transferrin receptors, and antibodies control cell infection and host range

HM Callaway, K Welsch, W Weichert, AB Allison… - Journal of …, 2018 - Am Soc Microbiol
… compared the binding of two well-characterized monoclonal anti-capsid antibodies and the
… TfR versus Fab14 binding to capsids to make our estimate of TfR copies bound per capsid. …

Viral capsid, antibody, and receptor interactions: experimental analysis of the antibody escape evolution of canine parvovirus

RA López-Astacio, OF Adu, DJ Goetschius… - Journal of …, 2023 - Am Soc Microbiol
… -2a capsids recognize many positions on the capsid surface, … -determining regions (CDRs)
contact multiple surface loops … uncharged residues to charged amino acids within the antigen …

Transferrin receptor binds virus capsid with dynamic motion

H Lee, HM Callaway, JO Cifuente… - Proceedings of the …, 2019 - National Acad Sciences
Canine parvovirus (CPV) is an important pathogen causing … close to the canine TfR (98.6%
amino acid sequence identity), … adjacent capsid structure contained multiple residues …

EVOLUTION OF FELINE AND CANINE PARVOVIRUSES: UNDERSTANDING THE CAPSID STRUCTURE, THE NATURAL VARIATION, AND THE ANTIBODY …

R Lopez-Astacio - 2023 - ecommons.cornell.edu
Multiple amino acids in the capsid structure of canine parvovirus coordinately determine
the canine host range and specific antigenic and hemagglutination properties. Journal of …

Simultaneous detection and differentiation of canine parvovirus and feline parvovirus by high resolution melting analysis

Y Sun, Y Cheng, P Lin, H Zhang, L Yi, M Tong… - BMC veterinary …, 2019 - Springer
… And we found two CPV-2c isolates from cats and no other … , that can simultaneously detect
many single-infection or co-… that had no effect on the amino acid Ala at residue 541 of the …

Roles of three amino acids of capsid proteins in mink enteritis parvovirus replication

Y Mao, J Su, J Wang, X Zhang, Q Hou, D Bian, W Liu - Virus research, 2016 - Elsevier
… To determine if introducing of these mutations into wt MEV-L altered its replication efficiency,
multiple-step growth curves were constructed over a 96 h period. F81 cells were infected …

Parvovirus Capsid Structures, Ligand Binding Interactions, and Endogenous Viral Elements

HM Callaway - 2018 - search.proquest.com
… This dissertation discusses mutations to the canine parvovirus (CPV) capsid that … Multiple
amino acids in the capsid structure of canine parvovirus coordinately determine the canine host …