[HTML][HTML] Neurogenin-1 overexpression increases the therapeutic effects of mesenchymal stem cells through enhanced engraftment in an ischemic rat brain

GH Kim, M Subash, JS Yoon, D Jo… - … of Stem Cells, 2020 - synapse.koreamed.org
Stem cell therapy is a promising strategy for treating neurological diseases but its … of the
stem cells. We determined whether neural induction of mesenchymal stem cells (MSCs) was …

Induction of neuronal-like phenotype in human mesenchymal stem cells by overexpression of Neurogenin1 and treatment with neurotrophins

L Schäck, S Budde, T Lenarz, C Krettek, G Gross… - Tissue and Cell, 2016 - Elsevier
therapies but might also present an option for improving the therapeutic efficacy of mesenchymal
stem cells… days in a neuronal induction medium with or without the growth factors BDNF …

[HTML][HTML] Comparison of MSC-Neurogenin1 administration modality in MCAO rat model

DH Shin, GH Kim, JS Lee, IS Joo… - Translational …, 2016 - degruyter.com
neuronal differentiation of mesenchymal stem cells showed the capability of neuronal induction
by … study compared the therapeutic effect after IC and IA administrations of stem cells. We …

[HTML][HTML] Resveratrol exerts dosage-dependent effects on the self-renewal and neural differentiation of hUC-MSCs

X Wang, S Ma, N Meng, N Yao, K Zhang, Q Li… - Molecules and cells, 2016 - Elsevier
Mesenchymal stem cells (MSCs) have been spotlighted in … and 10 μM RES before neural
induction reduced the expression of … after neural differentiation, the expression of Neurogenin1 (…

[HTML][HTML] Neuronal transcription program induced in hippocampal cells cocultured with bone marrow derived mesenchymal cells

S Majeed, A Aziz, SU Simjee - Heliyon, 2020 - cell.com
… FBS 5%) without any neural inducing chemical or growth factor. A large … increase in
expression of tubulin but slight expression for nestin (NPCS) was found validating neural stem cells

Effects of Growth Factors and the MicroRNA-183 Family on Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells Towards Auditory Neuron-Like …

G Farnoosh, MR Mahmoudian-Sani - Stem Cells and Cloning …, 2020 - Taylor & Francis
… Treatments with growth factors demonstrated a significant increase in neurogenin 1 (Ngn1)
and sex … following exposure to neural induction medium for 11days ( Figure 2B – E ). …

[HTML][HTML] Therapeutic utility of mesenchymal stromal cell (MSC)-based approaches in chronic neurodegeneration: a glimpse into underlying mechanisms, current status …

M Rahbaran, AO Zekiy, M Bahramali… - Cellular & Molecular …, 2022 - Springer
neural network secretion by hepatocyte growth factor … therapies have exerted therapeutic
benefits and mitigated symptoms of HD in preclinical models. Importantly, secretion of stem cell

The effect of Id1 gene silencing on the neural differentiation of MSCs

X Song, L Su, H Wei, Y Liu, H Yin, J Li… - Biotechnology & …, 2017 - Taylor & Francis
neural differentiation of mesenchymal stem cellsgrowth factor) and 10 ng/mL EGF (epidermal
growth factor). After one day, the pre-induction medium was replaced with neural induction

Anti-aging effects exerted by Tetramethylpyrazine enhances self-renewal and neuronal differentiation of rat bMSCs by suppressing NF-kB signaling

X Song, J Dai, H Li, Y Li, W Hao, Y Zhang… - Bioscience …, 2019 - portlandpress.com
therapeutic effects of mesenchymal stem cell (MSC)-based … the expression of neurogenin 1
(Ngn1), neuronal differentiation 1 … in the increasing state in the first 5 days of neural induction, …

[HTML][HTML] Role of mesenchymal stem cells in counteracting oxidative stress—related neurodegeneration

C Angeloni, M Gatti, C Prata, S Hrelia… - International journal of …, 2020 - mdpi.com
… suggest that neuronal therapeutic effect of stem cells is due to … that preserves neuronal
function. Moreover, appropriate … preconditioning with DFX improves therapeutic potential of AD-…