Omics in a digital world: the role of bioinformatics in providing new insights into human aging

S Dato, P Crocco, N Rambaldi Migliore… - Frontiers in …, 2021 - frontiersin.org
… Only one project combined two omics technologies, whereas we did not find any multi-omics
study. As in dbGaP, neither proteomics nor metabolomics data were present. …

Promising biomarkers of human aging: In search of a multi-omics panel to understand the aging process from a multidimensional perspective

NA Rivero-Segura, OY Bello-Chavolla… - Ageing research …, 2020 - Elsevier
… may be characterized by the multi-omics technologies. … studies describing transcriptomics
in different tissues and its relationship with aging, in this review, we will solely focus on studies

Multi-omics approaches to human biological age estimation

I Solovev, M Shaposhnikov, A Moskalev - Mechanisms of Ageing and …, 2020 - Elsevier
… based on data obtained using most omics technologies. … human aging is based on the
utilization of deep neural networks which may be trained on any type of appropriate (usually omics

Analytical tools to assess aging in humans: The rise of geri-omics

JP da Costa, T Rocha-Santos, AC Duarte - TrAC Trends in Analytical …, 2016 - Elsevier
… The omics technologies are at the forefront of aging research. … , more precisely, transcriptomics,
proteomics, and metabolomics contribute to the elucidation of the human aging process. …

Measuring biological age using omics data

J Rutledge, H Oh, T Wyss-Coray - Nature Reviews Genetics, 2022 - nature.com
ageing clocks built using omics data. Along the way, we attempt to clarify what ageing clocks
can actually measure, how to improve ageing … of ageing enabled by omics technologies. …

Emerging omics approaches in aging research

JS Lorusso, OA Sviderskiy… - Antioxidants & redox …, 2018 - liebertpub.com
omics techniques allowed identification of multiple regulatory non-coding RNAs and facilitated
studies of their role in aging. … Can human aging be slowed or reversed therapeutically? Is …

[HTML][HTML] Phenome and genome based studies into human ageing and longevity: An overview

PE Slagboom, N van den Berg, J Deelen - Biochimica Et Biophysica Acta …, 2018 - Elsevier
… Here we will discuss novel developments based on omics biomarkers, assays representing
Omics biomarkers In the past few years the omics technologies (transcriptomic, epigenomic, …

Aging biomarkers: from functional tests to multi‐omics approaches

KS Kudryashova, K Burka, AY Kulaga… - …, 2020 - Wiley Online Library
… been made to establish biomarkers to quantify human aging at the cellular, tissue, … to human
aging with an emphasis on biomarkers that take into account different mechanisms of aging

Aging Atlas: a multi-omics database for aging biology

Nucleic acids research, 2021 - academic.oup.com
aging database that provides access to large gene expression and regulation datasets
created by a variety of high-throughput omics technologies … of human aging at the protein level. …

Integrated multi-omics for novel aging biomarkers and antiaging targets

L Wu, X Xie, T Liang, J Ma, L Yang, J Yang, L Li, Y Xi… - Biomolecules, 2021 - mdpi.com
… on multi-omics technologies for aging biomarkers and novel antiaging targets. This multi-…
most complex methods for identifying human aging biomarkers. They can utilize any type of …