[HTML][HTML] SIRT1 suppresses adipogenesis by activating Wnt/β-catenin signaling in vivo and in vitro

Y Zhou, T Song, J Peng, Z Zhou, H Wei, R Zhou… - Oncotarget, 2016 - ncbi.nlm.nih.gov
… in adipose tissues of the SIRT1 +/− mice. The mRNA expression of PPARγ was higher in the
inguinal fat tissue … By contrast, the mRNA expression of PPARγ in the epididymal fat tissue

[HTML][HTML] Ups and downs: the PPARγ/p-PPARγ seesaw of follistatin-like 1 and integrin receptor signaling in adipogenesis

D Fang, X Shi, X Jia, C Yang, L Wang, B Du, T Lu… - Molecular …, 2022 - Elsevier
… in vitro and verified its function in promoting adipogenesis. In vivo studies, our adipose tissue-…
We comprehensively elucidated the role of FSTL1 in adipogenesis both in vitro and in vivo. …

Molecular regulation of adipogenesis and potential anti-adipogenic bioactive molecules

D Moseti, A Regassa, WK Kim - International journal of molecular …, 2016 - mdpi.com
… in vivo and in vitro [40]. In an in vivo study using mice, it was reported that PPARγ mRNA …
while a diet rich in fatty acids increases adipose tissue expression of PPARγ in normal mice and …

Synergistic activation of thermogenic adipocytes by a combination of PPARγ activation, SMAD3 inhibition and adrenergic receptor activation ameliorates metabolic …

T Matsumoto, S Kiuchi, T Murase - Diabetologia, 2019 - Springer
PPARγ), with thiazolidinediones (TZDs) acting as a ligand for PPARγ to induce browning of
white adipose tissue … in mammals or application to cultured adipocyte precursor cells [16, 17]. …

Role of the adipose PPARγ-adiponectin axis in susceptibility to stress and depression/anxiety-related behaviors

M Guo, C Li, Y Lei, S Xu, D Zhao, XY Lu - Molecular psychiatry, 2017 - nature.com
… in susceptibility and resilience to social defeat stress, we measured PPARγ mRNA and
protein levels in adipose tissue of susceptible and resilient mice in comparison with control mice. …

Adiponectin and PPAR: a setup for intricate crosstalk between obesity and non-alcoholic fatty liver disease

SM Ishtiaq, H Rashid, Z Hussain, MI Arshad… - Reviews in Endocrine …, 2019 - Springer
adipose tissue that culminates in most prevalent liver pathology named as non-alcoholic fatty
… Whereas, a recent study showed that HFD induces PPARγ expression by surplus free fatty

Addressing chemically-induced obesogenic metabolic disruption: selection of chemicals for in vitro human PPARα, PPARγ transactivation, and adipogenesis test …

E Ozcagli, B Kubickova, MN Jacobs - Frontiers in Endocrinology, 2024 - frontiersin.org
… white adipose tissue adipogenesis, PPARα and PPARγ … There are several types of fat
tissue in the human body, each … fat are white adipose tissue (WAT) and brown adipose tissue

Adipogenic role of alternatively activated macrophages in β-adrenergic remodeling of white adipose tissue

YH Lee, SN Kim, HJ Kwon… - American Journal …, 2016 - journals.physiology.org
… with Alox15 products accelerated adipogenic differentiation of adipocyte progenitors. These
adipocytes and timely generation of PPARγ ligands by M2 macrophages in adipose tissue

SIRT5 regulates brown adipocyte differentiation and browning of subcutaneous white adipose tissue

L Shuai, LN Zhang, BH Li, CL Tang, LY Wu, J Li… - Diabetes, 2019 - Am Diabetes Assoc
PPARγ is considered the master regulator of adipocyte … is essential for brown adipocyte
differentiation in vitro and has an impact on browning of subcutaneous adipose tissue in vivo. …

miRNA regulation of white and brown adipose tissue differentiation and function

NL Price, C Fernández-Hernando - … Acta (BBA)-Molecular and Cell Biology …, 2016 - Elsevier
… Overexpression of miR-130 has been demonstrated to inhibit differentiation of human pre-adipocytes
by targeting PPARγ, and expression of miR-130b was found to be reduced in …