… Genomes Project–imputed genotype data in up to ∼370,000 women, we identify 389
independent signals (P < 5 × 10 −8 ) for age at menarche… of the genetic regulation of puberty …

… find associations between specific loci and age at menarche. … Signals at 106 genomic
loci were identified in a GWAS … was also the allele associated with earlier age at menarche. …

… ancestry have identified at least 106 genetic loci for AM (He … >0.3, was used to evaluate
association between SNPs and AM or … mode, with allele frequency of 0.25 and per-allele effect of …

… age at menarche [−0.04 years per allele (3)], our study was clearly underpowered to observe
an association of … , which observed a strong association of genetic variations of LIN28B with …

… of the association between maternal and paternal alleles to identify … Our method revealed
parent-of-origin specific genome-wide … with latter age of menarche, or the maternal allele on …

… -Genome reference panel imputed genotype data on up to ~370,000 women and identify 389
independent signals (all P<5×10 −8 ) for age at menarche… the genetic regulation of puberty …

… ancestry revealed that at least 106 genetic loci explain AM [16,… carried out to test allelic
associations with AM using Plink [33]… In the present study, we replicated the association between …

… In this study, the association between maternal age at menarche (… allele T rs757647
KDM3B has the largest associations with … early onset of obesity and adrenal insufficiency [105,106]. …

… that there is an association between age at menarche (years) (… association between estrogen
17 β-estradiol (E2, genetic … BMD) correspond to the same allele, we harmonized the effect …

… Association between a SNP minor allele and AAM was analyzed using log-linear regression
assuming the three principal models (additive, recessive, and dominant). The year of birth, …