… To examine the direct binding of perlecan DV to integrin α5β1… of perlecan DV on PDGF-BB–induced
pericyte migration using … in endothelial cells through the binding of perlecan DV with …

… integrin and brain endothelial cell proliferation (57). Unlike with αvβ3, there is a compensatory
increase in α5β1 integrin when αvβ3 integrin … collagen IV and perlecan. Embryonically, α1 …

… Perlecan attached to the luminal surfaces of endothelial cells in … Perlecan domain V
also interacts with integrin α5β1 and promotes pericyte migration enhancing PDGF-BB-induced …

… via a competitive interaction (between DV and Aβ) with the α5β1 integrin on brain endothelial
cells [31… Increased brain vascular α5β1 integrin expression and amyloid burden that occurs …

… Perlecan domain V α5β1 integrin interactions promote pericyte migration, enhance PDGF-BB-induced …
administered perlecan domain V binds to this integrin on endothelial cells to bring …

… Endothelial cells of tumor blood vessels secrete PDGF, while … of endothelial cells, induces
their apoptosis and antagonizes … /Wnt signaling and α5β1-integrin, whereas endorepellin …

… intrinsic to these cells; rather they are induced and maintained … , an extracellular matrix
protein secreted by CNS pericytes, … brain and retina have the highest pericyte-to-endothelial cell …

… However, vascular injury, induced by the ligation of the distal … on brain endothelial cells
[17] via α5β1 integrin receptor, a … proteoglycan secreted by bovine aortic endothelial cells in …

… vascular endothelial growth factor secretion through activation of integrin α5β1 and its …
to show that α5β1 integrin regulates Ang1-induced endothelial cell migration and neovessel …

… , as revealed by collagen IV- or perlecan knockout mice, which are … Integrin α5β1 is the major
receptor for fibronectin and is … of integrins and associated proteins in endothelial cells (ECs)…