Dynamic positive end-expiratory pressure strategies using time and pressure recruitment at birth reduce early expression of lung injury in preterm lambs

DG Tingay, PM Pereira-Fantini… - … of Physiology-Lung …, 2022 - journals.physiology.org
… The aim is to quickly but carefully generate uniform aeration, … resuscitation guidelines suggest
that some PEEP be used for … at birth improves outcomes in newborn preterm lambs. Am J …

Delivery of positive end-expiratory pressure to preterm lambs using common resuscitation devices

M Thio, JA Dawson, KJ Crossley, TJ Moss… - Archives of Disease in …, 2019 - fn.bmj.com
… PEEP with faster inflation rates … preterm lambs. We also aimed to assess PEEP delivery
with and without gas flow, as we hypothesised that increasing flow within the SIB could increase

Impact of neonatal noninvasive resuscitation strategies on lung mechanics, tracheal pressure, and tidal volume in preterm lambs

D Bizzotto, MJ Dahl, C Veneroni… - … of Physiology-Lung …, 2024 - journals.physiology.org
… , leading to intratracheal positive end-expiratory pressure of … that SI helps to recruit the lung
rapidly, even when delivered 393 … that rapidly 486 aerating the lung of preterm lambs at birth …

Inflating pressure and not expiratory pressure initiates lung injury at birth in preterm lambs

DG Tingay, M Fatmous, K Kenna, G Dowse… - … Journal of Respiratory …, 2023 - atsjournals.org
preterm lambs that the use of dynamic PEEP results in better … of the dynamic positive
end-expiratory pressure without tidal … ), suggests that rapidly achieving aeration in the preterm

Gradual aeration at birth is more lung protective than a sustained inflation in preterm lambs

DG Tingay, PM Pereira-Fantini, R Oakley… - … journal of respiratory …, 2019 - atsjournals.org
… the lung using tidal inflations and positive end-expiratory pressure (… of PEEP during tidal
ventilation at birth improved short-term … of the preterm lung are not conducive to the rapid forced …

Aeration strategy at birth influences the physiological response to surfactant in preterm lambs

DG Tingay, A Togo, PM Pereira-Fantini… - Archives of Disease in …, 2019 - fn.bmj.com
… the importance of positive end-expiratory pressure (PEEP) to … We contend that rapidly achieving
aeration before tidal … duration at birth improves outcomes in newborn preterm lambs. Am …

Positive end-expiratory pressure in newborn resuscitation around term: a randomized controlled trial

K Holte, H Ersdal, J Eilevstjønn, Ø Gomo… - …, 2020 - publications.aap.org
… is recommended in international guidelines for resuscitation of preterm newborns. PEEP is
… 2 would rise faster in newborns ventilated with than without PEEP because of improved lung …

Early extubation to noninvasive respiratory support of former preterm lambs improves long-term respiratory outcomes

MJ Dahl, C Veneroni, A Lavizzari… - … of Physiology-Lung …, 2021 - journals.physiology.org
… recruitment during resuscitation because our experience is that the lung of preterm lambs
cavitates … Terminal respiratory units (TRU) have more and longer alveolar secondary septa and …

Respiratory mechanics during initial lung aeration at birth in the preterm lamb

C Veneroni, DG Tingay, KE McCall… - … of Physiology-Lung …, 2020 - journals.physiology.org
… by respiratory support with positive end-expiratory pressure (PEEP) has been proposed as
a resuscitation … The fast increase in R 5 and associated peak in the flow signal observed …

[HTML][HTML] Lung aeration reduces blood pressure surges caused by umbilical cord milking in preterm lambs

DA Blank, KJ Crossley, A Thiel, KA Rodgers… - Frontiers in …, 2023 - frontiersin.org
… in near term infants not requiring resuscitation (3–11). … The rapid increase in arterial blood
pressure (∼30%) and … at 7 ml/kg with a positive end-expiratory pressure of 5 cmH 2 O, rate of …