Proinflammatory cytokine response toward fungi but not bacteria in chronic granulomatous disease

RP Gazendam, A van de Geer… - Journal of Allergy and …, 2016 - jacionline.org
… show an enhanced proinflammatory cytokine response toward fungal but not toward bacterial
pathogens. … Patient C del exons 6_13 CYBB Recurrent bacterial and fungal infections, IBD …

Drug repurposing for the treatment of bacterial and fungal infections

A Miró-Canturri, R Ayerbe-Algaba… - Frontiers in microbiology, 2019 - frontiersin.org
… In the case of statin, simvastatin has been reported to modulate the production of proinflammatory
cytokines (IL-8 and CCL20) and Kruppel-like factors (an emerging group of immune …

HIF1α-dependent glycolysis promotes macrophage functional activities in protecting against bacterial and fungal infection

C Li, Y Wang, Y Li, Q Yu, X Jin, X Wang, A Jia, Y Hu… - Scientific reports, 2018 - nature.com
bacterial and fungal infections produced similar effects on macrophage functional differentiation.
HIF1α deficiency inhibited pro-inflammatory … and promotes pro-inflammatory cytokine

Role for IL-1 family cytokines in fungal infections

JS Griffiths, G Camilli, NK Kotowicz, J Ho… - Frontiers in …, 2021 - frontiersin.org
… similar biological activities, these two pro-inflammatory cytokines differ in several aspects.
IL-… has been described during models of viral and bacterial infection. In addition, IL-18BP is …

Understanding pathogenesis and care challenges of immune reconstitution inflammatory syndrome in fungal infections

S Dellière, R Guery, S Candon, B Rammaert, C Aguilar… - Journal of Fungi, 2018 - mdpi.com
… β-glucan from the fungal cell wall, eliciting pro-inflammatory cytokine release upon its …
pro-inflammatory activity through a TLR2 interaction [82]. Overall, the initial choice of antifungal

Leukocyte-released mediators in response to both bacterial and fungal infections trigger IFN pathways, independent of IL-1 and TNF-α, in endothelial cells

KTT Le, X Chu, M Jaeger, JA Plantinga… - Frontiers in …, 2019 - frontiersin.org
bacterial lipopeptides via Toll-like receptor signaling. Endothelial responses to infection
produce cytokines … , contribute to controlling infection (12). Therefore, based on the complexity of …

Immunotherapies against human bacterial and fungal infectious diseases: A review

H Qadri, AH Shah, M Alkhanani, A Almilaibary… - Frontiers in …, 2023 - frontiersin.org
… caused by extracellular and/or highly pro-inflammatory pathogenic bacterialcytokines are
now widely available, which has made it possible to treat different kinds of fungal infections, …

[HTML][HTML] Fungal infections: Pathogenesis, antifungals and alternate treatment approaches

GKK Reddy, AR Padmavathi… - Current Research in …, 2022 - Elsevier
… Overall immune evasion gives the benefit of anti-phagocytic effect, suppression of T cell
proliferation, proinflammatory cytokines and resistance to oxidative and nitrosative stresses. …

Fungal infections and new biologic therapies

S Vallabhaneni, TM Chiller - Current rheumatology reports, 2016 - Springer
infections including viral, bacterial, mycobacterial, fungal, and parasitic. Fungal infections,
especially invasive fungal infections … through production of proinflammatory cytokines and auto…

[HTML][HTML] Immune defence to invasive fungal infections: A comprehensive review

B Pathakumari, G Liang, W Liu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
… susceptibility to fungal infections, bacterial-fungal coinfections and … and initiate the pro-inflammatory
response and subsequently … of cytokines, which modulates the anti-fungal immune …