Calcium homeostasis in spermatozoa: Regulatory mechanisms and biological significance

AN Nakidkina, TI Kuzmina - … ), Supplement Series A: Membrane and Cell …, 2022 - Springer
human spermatozoa. At the same time, the biological role of such exchange consists in Ca
2… through the transporter that releases Ca 2+ to the cytosol in exchange for H + or Na + (NCX)…

Structure and function of ion channels regulating sperm motility—an overview

K Nowicka-Bauer, M Szymczak-Cendlak - International journal of …, 2021 - mdpi.com
… Like in every cell, ion homeostasis in spermatozoa is ensured by a … of sperm motility as Ca
2+ is a common secondary … for normal function of the Na + /H + -exchanger involved in the …

[HTML][HTML] Sperm Na+ K+-ATPase and Ca2+-ATPase activities: a potential predictive parameter of sperm motility disorder in infertile men

SW Lestari, MD Larasati… - Biomedical and …, 2018 - biomedpharmajournal.org
exchange of intracellular Na + for extracellular K + in sperm … which take part in the mechanism
regulating sperm motility. … for calcium homeostasis has a role in initiation of motility leading …

Role of calcium oscillations in sperm physiology

E Mata-Martínez, C Sánchez-Cárdenas, JC Chávez… - Biosystems, 2021 - Elsevier
… involved, their regulation and the physiological purpose of these … of [Ca 2+ ] i oscillatory
pathway that govern sperm motility. … K + -dependent Na + /Ca 2+ exchanger (NCKX) in the sperm

Sperm ion channels and transporters in male fertility and infertility

H Wang, LL McGoldrick, JJ Chung - Nature Reviews Urology, 2021 - nature.com
… the delicate and dynamic regulation of Ca 2+ homeostasis in sperm motility and fertility. …
and regulatory mechanisms of Na + /K + exchange and KSper is critical to understanding …

Flagellar pH homeostasis mediated by Na+/H+ exchangers regulates human sperm functions through coupling with CatSper and KSper activation

M Liang, N Ji, J Song, H Kang, X Zeng - Human Reproduction, 2024 - academic.oup.com
Human sperm motility and hyperactivation were severely … significantly, such as calcium
homeostasis, membrane potential, … the importance of NHEs in human sperm pH i regulation, and …

The role of sperm membrane potential and ion channels in regulating sperm function

FM Pinto, A Odriozola, L Candenas… - International Journal of …, 2023 - mdpi.com
Ca 2+ channels and suggest that VGSC might be involved in the regulation of the basal,
linear progressive sperm motility … Defective CFTR exchangers in human sperm alter Cl − and …

A review on the role of bicarbonate and proton transporters during sperm capacitation in mammals

A Delgado-Bermúdez, M Yeste, S Bonet… - International Journal of …, 2022 - mdpi.com
… essential role in regulating HCO 3 − homeostasis in sperm cells … have an essential role in
the regulation of sperm motility or in … exchanger does not participate in Ca 2+ influx towards the …

Na+/H+ Exchangers (NHEs) in Mammalian Sperm: Essential Contributors to Male Fertility

CC Gardner, PF James - International Journal of Molecular Sciences, 2023 - mdpi.com
role in the regulation of intracellular pH and motility of sperm. For … , inhibits rat sperm motility
suggesting the importance of Na + … a role in energy homeostasis in mammalian sperm which …

Molecular basis of human sperm capacitation

LC Puga Molina, GM Luque, PA Balestrini… - Frontiers in cell and …, 2018 - frontiersin.org
… , all data regarding human sperm function and regulation by … , the importance of this ion in
the regulation of sperm motility, … [Ca 2+ ]i are also regulated by the action of exchangers and …