Glycolaldehyde, an advanced glycation end products precursor, induces apoptosis via ROS-mediated mitochondrial dysfunction in renal mesangial cells
MJ Gu, JY Hyon, HW Lee, EH Han, Y Kim, YS Cha… - Antioxidants, 2022 - mdpi.com
… by interacting with AGEs that damage cells, leading to target … via the kidneys, which are
essential organs for AGE filtration [… with NAC, an ROS scavenger. This suggests that GA and GA-…
essential organs for AGE filtration [… with NAC, an ROS scavenger. This suggests that GA and GA-…
Interplay among oxidative stress, methylglyoxal pathway and S-glutathionylation
… the scavenging of ROS as well as of the reactive 2-oxoaldehydes … oxidation is fundamental
to block further damage on protein … is important for ROS-mediated signaling pathways. …
to block further damage on protein … is important for ROS-mediated signaling pathways. …
Safety issues of methylglyoxal and potential scavengers
… pathways, the glyoxalase system is the most important as the major detoxifying … also damage
the ability of insulin to bind or activate its receptor and probably lead to insulin resistance[35…
the ability of insulin to bind or activate its receptor and probably lead to insulin resistance[35…
Methylglyoxal–a signaling molecule in plant abiotic stress responses
… are mainly produced by ROS-mediated lipid peroxidation, … glyoxalase I-II system also have
important contributions to plant … assessing abiotic stress responses and resistance in plants. …
important contributions to plant … assessing abiotic stress responses and resistance in plants. …
Methylglyoxal, a highly reactive dicarbonyl compound, in diabetes, its vascular complications, and other age-related diseases
CG Schalkwijk, CDA Stehouwer - Physiological reviews, 2020 - journals.physiology.org
… intermediates of glycolysis induce damage to the vasculature and … itself induce insulin
resistance and β-cell dysfunction, and … Because GSH is also an essential cellular cofactor for Glo1 …
resistance and β-cell dysfunction, and … Because GSH is also an essential cellular cofactor for Glo1 …
Induction of mitochondrial apoptotic pathway in triple negative breast carcinoma cells by methylglyoxal via generation of reactive oxygen species
… by ROS mediated mitochondrial release of cytochrome c. … an important role in the MG induced
apoptosis of MDA MB 231 … Aggressive growth, evasion of apoptotic control, resistance to …
apoptosis of MDA MB 231 … Aggressive growth, evasion of apoptotic control, resistance to …
Cross‐Stress Tolerance in Plants: Molecular Mechanisms and Possible Involvement of Reactive Oxygen Species and Methylglyoxal Detoxification Systems
… to prevent cellular damage and to reestablish cellular … ) and methylglyoxal exhibit
important signaling functions and … ROS-scavenging systems in GB-mediated stress tolerance. …
important signaling functions and … ROS-scavenging systems in GB-mediated stress tolerance. …
[HTML][HTML] Methylglyoxal: an emerging signaling molecule in plant abiotic stress responses and tolerance
… The availability of cellular GSH is an important factor for MG detoxification via the … The
production of www.frontiersin.org is deleterious as it can cause oxidative damage to cellular …
production of www.frontiersin.org is deleterious as it can cause oxidative damage to cellular …
[HTML][HTML] Metformin inhibits methylglyoxal-induced retinal pigment epithelial cell death and retinopathy via AMPK-dependent mechanisms: reversing mitochondrial …
… In vital dye-induced damage of RPE and in retinitis pigmentosa … Cytosolic ROS-mediated
autophagy and subsequent … protection, we exclude the scavenger action of metformin as …
autophagy and subsequent … protection, we exclude the scavenger action of metformin as …
[PDF][PDF] Interplay among Oxidative Stress, Methylglyoxal Pathway and S-Glutathionylation. Antioxidants 2021, 10, 19
… (GSH), required for the scavenging of ROS as well as of the … oxidation is fundamental to
block further damage on protein … production is important for ROS-mediated signaling pathways…
block further damage on protein … production is important for ROS-mediated signaling pathways…