Melatonin enhanced the heavy metal-stress tolerance of pepper by mitigating the oxidative damage and reducing the heavy metal accumulation

MA Altaf, Y Hao, H Shu, MA Mumtaz, S Cheng… - Journal of Hazardous …, 2023 - Elsevier
… is crucial for improved resistance to HMs toxicity. … , glyoxalase defense system, and
methylglyoxal contents in pepper … mechanism and prevent ROS-mediated damage of thylakoid …

Approaches to enhancing antioxidant defense in plants

M Fujita, M Hasanuzzaman - Antioxidants, 2022 - mdpi.com
… and causing significant damage to essential cellular components such … However, the exact
pathways of ROS-mediated stress … be useful in directing efforts to increase cold tolerance [15]. …

[HTML][HTML] Oxidative stress, mitochondrial abnormalities and antioxidant defense in Ataxia-telangiectasia, Bloom syndrome and Nijmegen breakage syndrome

M Maciejczyk, B Mikoluc, B Pietrucha… - Redox Biology, 2017 - Elsevier
… , neurodegeneration and insulin resistance. Some of these … ROS-mediated oxidative DNA
damage [46]. HO-1 protects … glutathione (GSSG) and plasma methylglyoxal (MGlx). The levels …

Molecular and cellular mechanisms of cardiovascular disorders in diabetes

MS Shah, M Brownlee - Circulation research, 2016 - Am Heart Assoc
… identified increased methylglyoxal as an important element in … mechanisms include
ROS-mediated uncoupling of eNOS … and insulin resistance which together promote tissue injury

[HTML][HTML] Chronic hyperglycemia mediated physiological alteration and metabolic distortion leads to organ dysfunction, infection, cancer progression and other …

B Giri, S Dey, T Das, M Sarkar, J Banerjee… - Biomedicine & …, 2018 - Elsevier
… the pancreatic β-cell and inducing insulin resistance. Numerous … The requirement of glucose
is essential for every cell and … Chronic hyperglycemia mediates irreversible cell damage, …

Antiglycative activity and RAGE expression in Rett syndrome

V Cordone, A Pecorelli, M Benedusi, S Santini Jr… - Cells, 2019 - mdpi.com
… In order to evaluate the cellular susceptibility to methylglyoxal … that in RTT cells, the glyoxalase
scavenging system is unable to … damage were detected when we compared CTR and RTT …

Reactive oxygen species and cancer paradox: to promote or to suppress?

S Galadari, A Rahman, S Pallichankandy… - Free Radical Biology …, 2017 - Elsevier
… may provide a unique opportunity to eliminate cancer cellscell death pathways, or inhibiting
cancer cell resistance to … kill cancer cells and overcome drug resistance via enhancing ROS …

ROS modulation in crop plants under drought stress

G Verma, D Srivastava, P Tiwari… - … oxygen, nitrogen and …, 2019 - Wiley Online Library
… For example, glutathione‐induced drought stress tolerance can … damage and maintaining
methylglyoxal detoxification … point of crosstalk with ROS mediated signaling pathways. Ca2+ …

Mechanisms of nitric oxide crosstalk with reactive oxygen species scavenging enzymes during abiotic stress tolerance in plants

D Arora, P Jain, N Singh, H Kaur… - Free Radical …, 2016 - Taylor & Francis
… NO is also known to prevent ROS-mediated cytotoxic … helps in protecting cells against hydrogen
peroxide damage [Citation36… The present analysis thus provides a critical understanding …

[Retracted] Natural Antioxidants Improve the Vulnerability of Cardiomyocytes and Vascular Endothelial Cells under Stress Conditions: A Focus on Mitochondrial …

X Chang, Z Zhao, W Zhang, D Liu, C Ma… - … and Cellular …, 2021 - Wiley Online Library
cells from oxidative stress induced by methylglyoxal [22]. In … of ROS-mediated oxidative
stress injury are important ways to … , and cause insulin resistance. Triglyceride accumulation in …