Immunoinformatics approach to design novel subunit vaccine against the Epstein-Barr virus

AT Moin, RB Patil, T Tabassum, Y Araf… - Microbiology …, 2022 - Am Soc Microbiol
Epstein-Barr virus (EBV) is a lymphotropic virus responsible for … get infected with this
virus, and in most cases, this viral infectionsimulation of EBV was conducted using the C-ImmSim

Designing a vaccine-based therapy against Epstein-Barr virus-associated tumors using immunoinformatics approach

V Omoboyede, O Ibrahim, HI Umar, T Bello… - Computers in Biology …, 2022 - Elsevier
Epstein-Barr virus (EBV) is widely known due to its role in the etiology of infectious
Immune response profile of EBV vaccine generated by simulation using C-ImmSim server. …

Immunoinformatics design of novel peptide vaccines against Epstein-Barr virus with over 99% global population coverage: A Reverse Vaccinology approach

H Yousaf, A Naz - 2022 - researchsquare.com
… Immune Simulation For immune simulation, we used the classic C-IMMSIM server [38]. The
… Thus, for 3 doses, we initialized with 1050 simulation steps (which covers the time period of …

mRNA-based vaccine designing against Epstein-Barr virus to induce an immune response using immunoinformatic and molecular modelling approaches

HN Althurwi, KM Alharthy, FF Albaqami… - International Journal of …, 2022 - mdpi.com
… The C-immsim server uses a Position-specific Scoring Matrix … The simulation was set for three
injections, with an interval of … The C-ImmSim server sets a time-step scale for simulating an …

Immune epitopes identification and designing of a multi-epitope vaccine against bovine leukemia virus: a molecular dynamics and immune simulation approaches

A Samad, NS Meghla, Z Nain, TM Karpiński… - Cancer Immunology …, 2022 - Springer
… For analyzing the immunological response, the sequence of the vaccine construct was
submitted to the C-IMMSIM server and the immunological response results were downloaded [68]…

[HTML][HTML] Employing an immunoinformatics approach revealed potent multi-epitope based subunit vaccine for lymphocytic choriomeningitis virus

M Waqas, S Aziz, A Bushra, SA Halim, A Ali… - Journal of Infection and …, 2023 - Elsevier
… through molecular docking and molecular dynamics simulations. Computational immune
simulation of the designed vaccine antigen was performed using the C-ImmSim server. …

Pan-genome and reverse vaccinology approaches to design multi-epitope vaccine against Epstein-Barr virus associated with colorectal cancer

P Priyamvada, S Ramaiah - Immunologic Research, 2023 - Springer
… Immune simulation The in silico immune simulation was performed using a C-ImmSim server
that simulates immune response, determines immunogenicity, and generates an immune …

Immunoinformatic Execution and Design of an Anti-EpsteinBarr Virus Vaccine with Multiple Epitopes Triggering Innate and Adaptive Immune Responses

N Ahmed, AA Rabaan, ASS Alwashmi, H Albayat… - Microorganisms, 2023 - mdpi.com
C-IMMSIM server was accessed on 19 August 2022 through https://kraken.iac.rm.cnr.it/C-IMMSIM/…
response aligned with our immunological simulation objectives. The construct may be …

Immuno-informatics study identifies conserved T cell epitopes in non-structural proteins of Bluetongue virus serotypes: formulation of a computationally optimized next …

HB Kolla, M Dutt, A Kumar… - Frontiers in …, 2024 - frontiersin.org
… assessed in silico using the C-IMMSIM server. Structural modeling … -protein docking and
molecular dynamics simulations (MDS) to … Anoctamin 2 and Epstein-Barr virus nuclear antigen 1 …

Structural vaccinology, molecular simulation and immune simulation approaches to design multi-epitopes vaccine against John Cunningham virus

M Suleman, TA Khan, H Ejaz, S Maroof… - Microbial …, 2024 - Elsevier
… response, we used the C-ImmSim server (http://www.cbs.dtu.dk/services/CImmSim-10.1/
) accessed on July 1, 2022. This online immune simulation server uses the PSSM model to …