Real-world effectiveness of daclatasvir plus sofosbuvir and velpatasvir/sofosbuvir in hepatitis C genotype 2 and 3

PS Belperio, TA Shahoumian, TP Loomis, LA Mole… - Journal of …, 2019 - Elsevier
… Eligible individuals included all patients infected with HCV genotype 2 and genotype 3 who
initiated VA-prescribed DCV + SOF ± RBV or VEL/SOF ± RBV by the 31st March 2017 with …

Efficacy of sofosbuvir and velpatasvir, with and without ribavirin, in patients with hepatitis C virus genotype 3 infection and cirrhosis

R Esteban, JA Pineda, JL Calleja, M Casado… - Gastroenterology, 2018 - Elsevier
… We performed a phase 2 trial of 204 patients with genotype 3 HCV infection and …
sofosbuvir and velpatasvir for 12 weeks (n = 101) or sofosbuvir and velpatasvir plus ribavirin

[HTML][HTML] Efficacy of sofosbuvir, velpatasvir, and GS-9857 in patients with hepatitis C virus genotype 2, 3, 4, or 6 infections in an open-label, phase 2 trial

EJ Gane, KV Kowdley, D Pound, CAM Stedman… - Gastroenterology, 2016 - Elsevier
… In conclusion, sofosbuvir-velpatasvir plus GS-9857 is a safe and effective treatment in
patients with HCV genotypes 2, 3, 4, and 6, with and without compensated cirrhosis. High SVR …

Efficacy of 8 weeks of sofosbuvir, velpatasvir, and voxilaprevir in patients with chronic HCV infection: 2 phase 3 randomized trials

IM Jacobson, E Lawitz, EJ Gane, BE Willems… - Gastroenterology, 2017 - Elsevier
… of 8 weeks of sofosbuvir-velpatasvir-voxilaprevir to 12 weeks of sofosbuvir-velpatasvir using
a … POLARIS-3, which enrolled patients infected with HCV genotype 3 who had cirrhosis, …

High efficacy of sofosbuvir/velpatasvir and impact of baseline resistance‐associated substitutions in hepatitis C genotype 3 infection

J Von Felden, J Vermehren, P Ingiliz… - Alimentary …, 2018 - Wiley Online Library
… GT3 infection is associated with higher rates of liver steatosis, more rapid fibrosis … compared
to infection with other HCV genotypes.4-6 Historically, HCV GT3 infection was considered …

[HTML][HTML] Efficacy of sofosbuvir, velpatasvir, and GS-9857 in patients with genotype 1 hepatitis C virus infection in an open-label, phase 2 trial

E Lawitz, N Reau, F Hinestrosa, M Rabinovitz, E Schiff… - Gastroenterology, 2016 - Elsevier
… of the nucleotide polymerase inhibitor sofosbuvir, the NS5A inhibitor velpatasvir, and the
NS3/4A protease inhibitor GS-9857 in patients with hepatitis C virus genotype 1 infection. …

Resistance analysis in patients with genotype 1–6 HCV infection treated with sofosbuvir/velpatasvir in the phase III studies

C Hezode, N Reau, ES Svarovskaia, BP Doehle… - Journal of …, 2018 - Elsevier
… on global disease prevalence, especially in regions with high genotype diversity where
HCV genotyping and fibrosis staging are not part of routine medical care for HCV infection. …

Sofosbuvirvelpatasvir: A single-tablet treatment for hepatitis C infection of all genotypes

MM Miller - American Journal of Health-System Pharmacy, 2017 - academic.oup.com
HCV genotype 3 infection and cirrhosis, ribavirin must be added. In patients with HCV
genotype 2 or 3 infection who had treatment failure with the use of sofosbuvir plus ribavirin with or …

Real‐world clinical outcomes of sofosbuvir and velpatasvir treatment in HCV genotype 1‐and 2infected patients with decompensated cirrhosis: a nationwide …

T Tada, M Kurosaki, S Nakamura… - Journal of Medical …, 2021 - Wiley Online Library
… A total of 95 patients with chronic hepatitis C due to HCV genotype 1 and 2 infection who
underwent DAA treatment with the 12-week SOF/VEL regimen in our network of hospitals …

Sofosbuvir and velpatasvir for the treatment of hepatitis C virus in patients coinfected with human immunodeficiency virus type 1: an open-label, phase 3 study

D Wyles, N Bräu, S Kottilil, ES Daar… - Clinical Infectious …, 2017 - academic.oup.com
… limited by the small number of patients we enrolled with cirrhosis as well as HCV genotypes
1b, 2, 3, and 4, as well as the fact that no patients with HCV genotype 5 or 6 were enrolled. …